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Hyperphosphatemia with elevated serum PTH and FGF23, reduced 1,25(OH)(2)D and normal FGF7 concentrations characterize patients with CKD
BACKGROUND: Hyperphosphatemia confers adverse cardiovascular outcomes, and commonly occurs in late-stage CKD. Fibroblast growth factor 7 (FGF7) is a phosphaturic peptide which decreases renal phosphate transport in vitro and in vivo. Serum FGF7 concentrations are reduced in hyperphosphatemic patient...
Autores principales: | Kritmetapak, Kittrawee, Losbanos, Louis, Berent, Taylor E., Ashrafzadeh-Kian, Susan L., Algeciras-Schimnich, Alicia, Hines, Jolaine M., Singh, Ravinder J., Kumar, Rajiv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011073/ https://www.ncbi.nlm.nih.gov/pubmed/33784965 http://dx.doi.org/10.1186/s12882-021-02311-3 |
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