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Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond
Radiotherapy is an essential component of multi-modality treatment of glioblastoma (GBM). However, treatment failure and recurrence are frequent and give rise to the dismal prognosis of this aggressive type of primary brain tumor. A high level of inherent treatment resistance is considered to be the...
Autores principales: | Orth, Michael, Albrecht, Valerie, Seidl, Karin, Kinzel, Linda, Unger, Kristian, Hess, Julia, Kreutzer, Lisa, Sun, Na, Stegen, Benjamin, Nieto, Alexander, Maas, Jessica, Winssinger, Nicolas, Friedl, Anna A., Walch, Axel K., Belka, Claus, Zitzelsberger, Horst, Niyazi, Maximilian, Lauber, Kirsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011354/ https://www.ncbi.nlm.nih.gov/pubmed/33816244 http://dx.doi.org/10.3389/fonc.2021.612354 |
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