Exosomes from BM-MSCs promote acute myeloid leukemia cell proliferation, invasion and chemoresistance via upregulation of S100A4

BACKGROUND: BM-MSCs play an important role in cancer development through the release of cytokines or exosomes. Studies have shown that extracellular exosomes derived from BM-MSCs are a key pro-invasive factor. However, how BM-MSC-exos influence AML cell proliferation, invasion and chemoresistance re...

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Detalles Bibliográficos
Autores principales: Lyu, Tianxin, Wang, Yinuo, Li, Ding, Yang, Hui, Qin, Bin, Zhang, Wenli, Li, Zhiyue, Cheng, Cheng, Zhang, Binglei, Guo, Rongqun, Song, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011411/
https://www.ncbi.nlm.nih.gov/pubmed/33789743
http://dx.doi.org/10.1186/s40164-021-00220-7

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