Cargando…

A Clot Twist: Extreme Variation in Coagulotoxicity Mechanisms in Mexican Neotropical Rattlesnake Venoms

Rattlesnakes are a diverse clade of pit vipers (snake family Viperidae, subfamily Crotalinae) that consists of numerous medically significant species. We used validated in vitro assays measuring venom-induced clotting time and strength of any clots formed in human plasma and fibrinogen to assess the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seneci, Lorenzo, Zdenek, Christina N., Chowdhury, Abhinandan, Rodrigues, Caroline F. B., Neri-Castro, Edgar, Bénard-Valle, Melisa, Alagón, Alejandro, Fry, Bryan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011430/ https://www.ncbi.nlm.nih.gov/pubmed/33815366 http://dx.doi.org/10.3389/fimmu.2021.612846

Ejemplares similares

A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms
por: Grashof, Dwin, et al.
Publicado: (2020)

Neotropical Rattlesnake (Crotalus simus) Venom Pharmacokinetics in Lymph and Blood Using an Ovine Model
por: Neri-Castro, Edgar, et al.
Publicado: (2020)

Pan-American Lancehead Pit-Vipers: Coagulotoxic Venom Effects and Antivenom Neutralisation of Bothrops asper and B. atrox Geographical Variants
por: Bourke, Lachlan A., et al.
Publicado: (2021)

Ontogenetic Change in the Venom of Mexican Black-Tailed Rattlesnakes (Crotalus molossus nigrescens)
por: Borja, Miguel, et al.
Publicado: (2018)

Detection and quantification of a β-neurotoxin (crotoxin homologs) in the venom of the rattlesnakes Crotalus simus, C. culminatus and C. tzabcan from Mexico
por: Neri-Castro, Edgar, et al.
Publicado: (2019)

Biological and Biochemical Characterization of Coronado Island Rattlesnake (Crotalus helleri caliginis) Venom and Antivenom Neutralization
por: Franco-Servín, Cristian, et al.
Publicado: (2021)

Clinical and Evolutionary Implications of Dynamic Coagulotoxicity Divergences in Bothrops (Lancehead Pit Viper) Venoms
por: Bourke, Lachlan Allan, et al.
Publicado: (2022)

Venom Ontogeny in the Mexican Lance-Headed Rattlesnake (Crotalus polystictus)
por: Mackessy, Stephen P., et al.
Publicado: (2018)

Differential Antivenom and Small-Molecule Inhibition of Novel Coagulotoxic Variations in Atropoides, Cerrophidion, Metlapilcoatlus, and Porthidium American Viperid Snake Venoms
por: Jones, Lee, et al.
Publicado: (2022)

Venomous Landmines: Clinical Implications of Extreme Coagulotoxic Diversification and Differential Neutralization by Antivenom of Venoms within the Viperid Snake Genus Bitis
por: Youngman, Nicholas J., et al.
Publicado: (2019)

Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)
por: Bittenbinder, Mátyás A., et al.
Publicado: (2018)

Coagulotoxicity of Bothrops (Lancehead Pit-Vipers) Venoms from Brazil: Differential Biochemistry and Antivenom Efficacy Resulting from Prey-Driven Venom Variation
por: Sousa, Leijiane F., et al.
Publicado: (2018)

Iodine an Antidote to the Venom of the Rattlesnake
por: Whitmire, James S.
Publicado: (1860)

Efficacy and Limitations of Chemically Diverse Small-Molecule Enzyme-Inhibitors against the Synergistic Coagulotoxic Activities of Bitis Viper Venoms
por: Youngman, Nicholas J., et al.
Publicado: (2022)

Evidence for Resistance to Coagulotoxic Effects of Australian Elapid Snake Venoms by Sympatric Prey (Blue Tongue Skinks) but Not by Predators (Monitor Lizards)
por: Youngman, Nicholas J., et al.
Publicado: (2021)

Biochemical and immunochemical characterization of venoms from snakes of the genus Agkistrodon
por: Román-Domínguez, Luis, et al.
Publicado: (2019)

In vitro hemotoxic, α-neurotoxic and vasculotoxic effects of the Mexican black-tailed rattlesnake (Crotalus molossus nigrescens) venom
por: Meléndez-Martínez, David, et al.
Publicado: (2017)

Diverse and Dynamic Alpha-Neurotoxicity Within Venoms from the Palearctic Viperid Snake Clade of Daboia, Macrovipera, Montivipera, and Vipera
por: Chowdhury, Abhinandan, et al.
Publicado: (2022)

A Meta-Analysis of the Protein Components in Rattlesnake Venom
por: Deshwal, Anant, et al.
Publicado: (2021)

The venom-gland transcriptome of the eastern diamondback rattlesnake (Crotalus adamanteus)
por: Rokyta, Darin R, et al.
Publicado: (2012)

The genetics of venom ontogeny in the eastern diamondback rattlesnake (Crotalus adamanteus)
por: Rokyta, Darin R., et al.
Publicado: (2017)

The Action of Rattlesnake Venom upon the Bactericidal Power of the Blood-serum
por: Ewing, Charles B.
Publicado: (1895)

Varanid Lizard Venoms Disrupt the Clotting Ability of Human Fibrinogen through Destructive Cleavage
por: Dobson, James S., et al.
Publicado: (2019)

Researches upon the Venom of the Rattlesnake, with an Investigation of the Anatomy and Physiology of the Organs Concerned
Publicado: (1868)

The Relative Efficacy of Chemically Diverse Small-Molecule Enzyme-Inhibitors Against Anticoagulant Activities of African Spitting Cobra (Naja Species) Venoms
por: Chowdhury, Abhinandan, et al.
Publicado: (2021)

Rattlesnake Crotalus molossus nigrescens venom induces oxidative stress on human erythrocytes
por: Meléndez-Martínez, David, et al.
Publicado: (2017)

The Rattlesnake
Publicado: (1889)

The genesis of an exceptionally lethal venom in the timber rattlesnake (Crotalus horridus) revealed through comparative venom-gland transcriptomics
por: Rokyta, Darin R, et al.
Publicado: (2013)

The venom of South American rattlesnakes inhibits macrophage functions and is endowed with anti-inflammatory properties
por: Silva, Maria C. C. de Sousa e, et al.
Publicado: (1996)

Phenotypic Variation in Mojave Rattlesnake (Crotalus scutulatus) Venom Is Driven by Four Toxin Families
por: Strickland, Jason L., et al.
Publicado: (2018)

Gradual and Discrete Ontogenetic Shifts in Rattlesnake Venom Composition and Assessment of Hormonal and Ecological Correlates
por: Schonour, Richard B., et al.
Publicado: (2020)

A novel activity on thymocytes cells exerted by the rattlesnake (Crotalus durissus cumanensis) venom
por: Pulido-Méndez, María M., et al.
Publicado: (2021)

The Rattlesnake Poison
Publicado: (1866)

On the Bite of the Rattlesnake
por: Woodhouse, S. W.
Publicado: (1852)

Rattlesnakes and Their Bites
Publicado: (1876)

The Bite of the Rattlesnake
por: Phelps, Chas. A.
Publicado: (1848)

Fangs of the Rattlesnake
Publicado: (1883)

Phylogeny-Based Comparative Analysis of Venom Proteome Variation in a Clade of Rattlesnakes (Sistrurus sp.)
por: Gibbs, H. Lisle, et al.
Publicado: (2013)

Capillary damage in the area postrema by venom of the northern black-tailed rattlesnake (Crotalus molossus molossus)
por: Meléndez-Martínez, David, et al.
Publicado: (2014)

Evidence for divergent patterns of local selection driving venom variation in Mojave Rattlesnakes (Crotalus scutulatus)
por: Strickland, Jason L., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1uhkr5hagtbitkc97bicp9eqf6