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Characteristics of colorectal carcinoma patients with PMS2 defects detected by immunohistochemistry
Lynch syndrome is the most prevalent form of familial colorectal cancer (CRC) and is caused by pathogenic germline mismatch repair (MMR) gene mutations. MLH1, MSH2 and MSH6 mutations have been well studied, but the rate and characteristics of PMS2 mutations are rare, especially in China. This study...
Autores principales: | Zeng, Zhijun, Yan, Qijia, Chen, Guodong, Zhang, Xiaoli, Huang, Jia, Fu, Kai, Peng, Xiuda, Xiao, Shuai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011511/ https://www.ncbi.nlm.nih.gov/pubmed/32826709 http://dx.doi.org/10.1097/CEJ.0000000000000620 |
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