Identification of FDA approved drugs against SARS-CoV-2 RNA dependent RNA polymerase (RdRp) and 3-chymotrypsin-like protease (3CLpro), drug repurposing approach

The RNA-dependent RNA polymerase (RdRp) and 3C-like protease (3CLpro) from SARS-CoV-2 play crucial roles in the viral life cycle and are considered the most promising targets for drug discovery against SARS-CoV-2. In this study, FDA-approved drugs were screened to identify the probable anti-RdRp and...

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Detalles Bibliográficos
Autores principales: Molavi, Zahra, Razi, Sara, Mirmotalebisohi, Seyed Amir, Adibi, Amirjafar, Sameni, Marzieh, Karami, Farshid, Niazi, Vahid, Niknam, Zahra, Aliashrafi, Morteza, Taheri, Mohammad, Ghafouri-Fard, Soudeh, Jeibouei, Shabnam, Mahdian, Soodeh, Zali, Hakimeh, Ranjbar, Mohammad Mehdi, Yazdani, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Masson SAS. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011644/
https://www.ncbi.nlm.nih.gov/pubmed/34311539
http://dx.doi.org/10.1016/j.biopha.2021.111544

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