Cargando…

Oncogenic role of abnormal spindle-like microcephaly-associated protein in lung adenocarcinoma

Lung adenocarcinoma (LUAD) is a common malignant cancer worldwide. It is urgent to explore its underlying molecular mechanism and identify novel diagnostic biomarkers. Abnormal spindle-like microcephaly (ASPM) has recently received considerable attention due to its function in tumor progression. How...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jiang, Liang, Jinghui, Li, Haixia, Han, Jingyi, Jiang, Jin, Li, Yongmeng, Feng, Zitong, Zhao, Renchang, Tian, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012022/ https://www.ncbi.nlm.nih.gov/pubmed/33786609 http://dx.doi.org/10.3892/ijo.2021.5203

Ejemplares similares

Mex3a interacts with LAMA2 to promote lung adenocarcinoma metastasis via PI3K/AKT pathway
por: Liang, Jinghui, et al.
Publicado: (2020)

Let-7b-3p inhibits tumor growth and metastasis by targeting the BRF2-mediated MAPK/ERK pathway in human lung adenocarcinoma
por: Li, Yongmeng, et al.
Publicado: (2021)

Cyclin O promotes lung cancer progression and cetuximab resistance via cell cycle regulation and CDK13 interaction
por: Jiang, Jin, et al.
Publicado: (2023)

Overexpression of abnormal spindle-like microcephaly-associated (ASPM) increases tumor aggressiveness and predicts poor outcome in patients with lung adenocarcinoma
por: Feng, Zhenxing, et al.
Publicado: (2021)

EIF4A3 Acts on the PI3K–AKT–ERK1/2–P70S6K Pathway through FLOT1 to Influence the Development of Lung Adenocarcinoma
por: Yu, Wenhao, et al.
Publicado: (2023)

A Novel Frameshift Mutation in Abnormal Spindle-Like Microcephaly (ASPM) Gene in an Iranian Patient with Primary Microcephaly: A Case Report
por: BAZGIR, Afsaneh, et al.
Publicado: (2019)

MCTS1 promotes the development of lung adenocarcinoma by regulating E2F1 expression
por: Gao, Cun, et al.
Publicado: (2021)

Abnormal spindle-like microcephaly-associated protein (ASPM) contributes to the progression of Lung Squamous Cell Carcinoma (LSCC) by regulating CDK4
por: Yuan, Ya-Jing, et al.
Publicado: (2020)

Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease
por: Li, Rui, et al.
Publicado: (2017)

Abnormal spindle-like microcephaly-associated protein (ASPM) contributes to the progression of Lung Squamous Cell Carcinoma (LSCC) by regulating CDK4: Erratum
por: Yuan, Ya-Jing, et al.
Publicado: (2023)

Integrated bioinformatics analysis of differentially expressed genes and immune cell infiltration characteristics in Esophageal Squamous cell carcinoma
por: Feng, Zitong, et al.
Publicado: (2021)

Microcephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindle
por: Ito, Ami, et al.
Publicado: (2015)

Circular RNA hsa-circ-000881 suppresses the progression of lung adenocarcinoma in vitro via a miR-665/PRICKLE2 axis
por: Huang, Chu, et al.
Publicado: (2021)

Negatively Regulated by miR-29c-3p, MTFR1 Promotes the Progression and Glycolysis in Lung Adenocarcinoma via the AMPK/mTOR Signalling Pathway
por: Li, Yongmeng, et al.
Publicado: (2021)

Extrachromosomal circular DNAs are common and functional in esophageal squamous cell carcinoma
por: Sun, Zhenguo, et al.
Publicado: (2021)

Corrigendum: Negatively regulated by miR-29c-3p, MTFR1 promotes the progression and glycolysis in lung adenocarcinoma via the AMPK/mTOR signalling pathway
por: Li, Yongmeng, et al.
Publicado: (2022)

Abnormal spindle-like microcephaly-associated protein enhances cell invasion through Wnt/β-catenin-dependent regulation of epithelial-mesenchymal transition in non-small cell lung cancer cells
por: Xia, Chunwei, et al.
Publicado: (2021)

DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation
por: Lu, Li, et al.
Publicado: (2016)

The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus
por: Shohayeb, Belal, et al.
Publicado: (2020)

Extra Spindle Pole Bodies-Like 1 Serves as a Prognostic Biomarker and Promotes Lung Adenocarcinoma Metastasis
por: Nie, Zhi, et al.
Publicado: (2022)

Human Microcephaly Protein RTTN Is Required for Proper Mitotic Progression and Correct Spindle Position
por: Chou, En-Ju, et al.
Publicado: (2021)

Abnormal centrosome and spindle morphology in a patient with autosomal recessive primary microcephaly type 2 due to compound heterozygous WDR62 gene mutation
por: Farag, Heba Gamal, et al.
Publicado: (2013)

The neurodevelopmental transcriptome of the Drosophila melanogaster microcephaly gene abnormal spindle reveals a role for temporal transcription factors and the immune system in regulating brain size
por: Mannino, Maria C., et al.
Publicado: (2023)

UHMK1 promotes lung adenocarcinoma oncogenesis by regulating the PI3K/AKT/mTOR signaling pathway
por: Li, Yongmeng, et al.
Publicado: (2023)

Microcephaly
por: Hanzlik, Emily, et al.
Publicado: (2017)

A comprehensive study on the oncogenic mutation and molecular pathology in Chinese lung adenocarcinoma patients
por: Zhang, Xilin, et al.
Publicado: (2020)

Circular RNA circTRPS1-2 inhibits the proliferation and migration of esophageal squamous cell carcinoma by reducing the production of ribosomes
por: Zhao, Renchang, et al.
Publicado: (2023)

Microcephaly-associated protein WDR62 shuttles from the Golgi apparatus to the spindle poles in human neural progenitors
por: Dell'Amico, Claudia, et al.
Publicado: (2023)

Mutations in the β-Tubulin Gene TUBB5 Cause Microcephaly with Structural Brain Abnormalities
por: Breuss, Martin, et al.
Publicado: (2012)

Developmental protein kinase C hyper-activation results in microcephaly and behavioral abnormalities in zebrafish
por: Liu, Taian, et al.
Publicado: (2018)

Oncogenic RIT1 mutations in lung adenocarcinoma
por: Berger, A H, et al.
Publicado: (2014)

Genetic analysis and prenatal diagnosis in a Chinese with growth retardation, abnormal liver function, and microcephaly
por: Zhao, Peiwei, et al.
Publicado: (2021)

The mitotic spindle-related seven-gene predicts the prognosis and immune microenvironment of lung adenocarcinoma
por: Shen, Ruxin, et al.
Publicado: (2023)

Mex3a promotes oncogenesis through the RAP1/MAPK signaling pathway in colorectal cancer and is inhibited by hsa‐miR‐6887‐3p
por: Li, Haixia, et al.
Publicado: (2021)

LncRNA LINC00511 plays an oncogenic role in lung adenocarcinoma by regulating PKM2 expression via sponging miR‐625‐5p
por: Xue, Jinghui, et al.
Publicado: (2020)

Advances in lung adenocarcinoma: A novel perspective on prognoses and immune responses of CENPO as an oncogenic superenhancer
por: Shi, Tongdong, et al.
Publicado: (2023)

RDM1 plays an oncogenic role in human lung adenocarcinoma cells
por: Tong, Lu, et al.
Publicado: (2018)

Identification of Abnormal Spindle Microtubule Assembly as a Promising Therapeutic Target for Osteosarcoma
por: Lin, Peng, et al.
Publicado: (2020)

Population surveillance for microcephaly
por: Kirby, Russell S
Publicado: (2016)

Microcephaly in Neurometabolic Diseases
por: Kempińska, Wiktoria, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tduh47c6b2pp602tkbnj88fcrf