Increased longevity due to sexual activity in mole-rats is associated with transcriptional changes in the HPA stress axis

Sexual activity and/or reproduction are associated with a doubling of life expectancy in the long-lived rodent genus Fukomys. To investigate the molecular mechanisms underlying this phenomenon, we analyzed 636 RNA-seq samples across 15 tissues. This analysis suggests that changes in the regulation o...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahm, Arne, Platzer, Matthias, Koch, Philipp, Henning, Yoshiyuki, Bens, Martin, Groth, Marco, Burda, Hynek, Begall, Sabine, Ting, Saskia, Goetz, Moritz, Van Daele, Paul, Staniszewska, Magdalena, Klose, Jasmin Mona, Costa, Pedro Fragoso, Hoffmann, Steve, Szafranski, Karol, Dammann, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012063/
https://www.ncbi.nlm.nih.gov/pubmed/33724179
http://dx.doi.org/10.7554/eLife.57843

Ejemplares similares

Ejemplares similares