Determination of Risk Groups for the Covid-19 Underlying Deseases

For every disease, there is a certain set of genes whose mutations increase the risk of illness development. DNA sequencing of sick and healthy individuals results in the determination of genes related to certain diseases. Efficient procedures are described in order to determine point mutations in g...

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Detalles Bibliográficos
Autores principales: Vagis, A. A., Gupal, A. M., Sergienko, I. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012156/
https://www.ncbi.nlm.nih.gov/pubmed/33821122
http://dx.doi.org/10.1007/s10559-021-00347-9
Descripción
Sumario:For every disease, there is a certain set of genes whose mutations increase the risk of illness development. DNA sequencing of sick and healthy individuals results in the determination of genes related to certain diseases. Efficient procedures are described in order to determine point mutations in gene sequences of the examined patients. The optimal Bayesian procedure is used to determine risk groups for certain diseases, including the ones that underlie COVID-19.

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