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Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial

AIMS/HYPOTHESIS: Oral administration of antigen can induce immunological tolerance. Insulin is a key autoantigen in childhood type 1 diabetes. Here, oral insulin was given as antigen-specific immunotherapy before the onset of autoimmunity in children from age 6 months to assess its safety and immune...

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Detalles Bibliográficos
Autores principales:	Assfalg, Robin, Knoop, Jan, Hoffman, Kristi L., Pfirrmann, Markus, Zapardiel-Gonzalo, Jose Maria, Hofelich, Anna, Eugster, Anne, Weigelt, Marc, Matzke, Claudia, Reinhardt, Julia, Fuchs, Yannick, Bunk, Melanie, Weiss, Andreas, Hippich, Markus, Halfter, Kathrin, Hauck, Stefanie M., Hasford, Jörg, Petrosino, Joseph F., Achenbach, Peter, Bonifacio, Ezio, Ziegler, Anette-Gabriele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012335/ https://www.ncbi.nlm.nih.gov/pubmed/33515070 http://dx.doi.org/10.1007/s00125-020-05376-1

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