An automated and high-throughput-screening compatible pluripotent stem cell-based test platform for developmental and reproductive toxicity assessment of small molecule compounds

The embryonic stem cell test (EST) represents the only validated and accepted in vitro system for the detection and classification of compounds according to their developmental and reproductive teratogenic potency. The widespread implementation of the EST, however, in particular for routine applicat...

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Detalles Bibliográficos
Autores principales: Witt, Gesa, Keminer, Oliver, Leu, Jennifer, Tandon, Rashmi, Meiser, Ina, Willing, Anne, Winschel, Ingo, Abt, Jana-Christin, Brändl, Björn, Sébastien, Isabelle, Friese, Manuel A., Müller, Franz-Josef, Neubauer, Julia C., Claussen, Carsten, Zimmermann, Heiko, Gribbon, Philip, Pless, Ole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012336/
https://www.ncbi.nlm.nih.gov/pubmed/32564278
http://dx.doi.org/10.1007/s10565-020-09538-0

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