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The future of meniscus science: international expert consensus

PURPOSE: The purpose of this study was to evaluate the main focus areas for research and development for furthering the state of meniscus science in 2021. METHODS: An electronic survey including 10 questions was sent in a blind fashion to the faculty members of the 5(th) International Conference on...

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Autores principales: DePhillipo, Nicholas N., LaPrade, Robert F., Zaffagnini, Stefano, Mouton, Caroline, Seil, Romain, Beaufils, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012449/
https://www.ncbi.nlm.nih.gov/pubmed/33791890
http://dx.doi.org/10.1186/s40634-021-00345-y
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author DePhillipo, Nicholas N.
LaPrade, Robert F.
Zaffagnini, Stefano
Mouton, Caroline
Seil, Romain
Beaufils, Philippe
author_facet DePhillipo, Nicholas N.
LaPrade, Robert F.
Zaffagnini, Stefano
Mouton, Caroline
Seil, Romain
Beaufils, Philippe
author_sort DePhillipo, Nicholas N.
collection PubMed
description PURPOSE: The purpose of this study was to evaluate the main focus areas for research and development for furthering the state of meniscus science in 2021. METHODS: An electronic survey including 10 questions was sent in a blind fashion to the faculty members of the 5(th) International Conference on Meniscus Science and Surgery. These faculty served as an expert consensus on the future of research and development areas of meniscus science. Survey responses were analyzed using descriptive statistics and ranking weighted averages were calculated to score survey questions. RESULTS: Of the 82 faculty, 76 (93%) from 18 different countries completed the survey (84% male, 16% female). The highest ranked future research and development focus areas were meniscus repair, biologics, osteotomy procedures, addressing meniscus extrusion, and the development of new therapies for the prevention of posttraumatic osteoarthritis. Currently, the most ‘valuable’ type of biologic reported for meniscus treatment was platelet-rich plasma. The main reported global research limitation was a lack of long-term clinical outcomes data. The most promising emerging medical technologies for improving meniscus science were 3-D printing, personalized medicine, and artificial implants. CONCLUSIONS: This survey suggests that the future of meniscus science should be focused on meniscal preservation techniques through meniscus repair, addressing meniscal extrusion, and the use of orthobiologics. The lack of long-term clinical outcomes was the main reported research limitation globally for meniscus treatment. Future product development utilizing emerging medical technologies suggest the use of 3-D printing for meniscal transplants/scaffolds, personalized treatment, and bioengineering for artificial implants. LEVEL OF EVIDENCE: Level V. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40634-021-00345-y.
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spelling pubmed-80124492021-04-16 The future of meniscus science: international expert consensus DePhillipo, Nicholas N. LaPrade, Robert F. Zaffagnini, Stefano Mouton, Caroline Seil, Romain Beaufils, Philippe J Exp Orthop Original Paper PURPOSE: The purpose of this study was to evaluate the main focus areas for research and development for furthering the state of meniscus science in 2021. METHODS: An electronic survey including 10 questions was sent in a blind fashion to the faculty members of the 5(th) International Conference on Meniscus Science and Surgery. These faculty served as an expert consensus on the future of research and development areas of meniscus science. Survey responses were analyzed using descriptive statistics and ranking weighted averages were calculated to score survey questions. RESULTS: Of the 82 faculty, 76 (93%) from 18 different countries completed the survey (84% male, 16% female). The highest ranked future research and development focus areas were meniscus repair, biologics, osteotomy procedures, addressing meniscus extrusion, and the development of new therapies for the prevention of posttraumatic osteoarthritis. Currently, the most ‘valuable’ type of biologic reported for meniscus treatment was platelet-rich plasma. The main reported global research limitation was a lack of long-term clinical outcomes data. The most promising emerging medical technologies for improving meniscus science were 3-D printing, personalized medicine, and artificial implants. CONCLUSIONS: This survey suggests that the future of meniscus science should be focused on meniscal preservation techniques through meniscus repair, addressing meniscal extrusion, and the use of orthobiologics. The lack of long-term clinical outcomes was the main reported research limitation globally for meniscus treatment. Future product development utilizing emerging medical technologies suggest the use of 3-D printing for meniscal transplants/scaffolds, personalized treatment, and bioengineering for artificial implants. LEVEL OF EVIDENCE: Level V. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40634-021-00345-y. Springer Berlin Heidelberg 2021-03-31 /pmc/articles/PMC8012449/ /pubmed/33791890 http://dx.doi.org/10.1186/s40634-021-00345-y Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Paper
DePhillipo, Nicholas N.
LaPrade, Robert F.
Zaffagnini, Stefano
Mouton, Caroline
Seil, Romain
Beaufils, Philippe
The future of meniscus science: international expert consensus
title The future of meniscus science: international expert consensus
title_full The future of meniscus science: international expert consensus
title_fullStr The future of meniscus science: international expert consensus
title_full_unstemmed The future of meniscus science: international expert consensus
title_short The future of meniscus science: international expert consensus
title_sort future of meniscus science: international expert consensus
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012449/
https://www.ncbi.nlm.nih.gov/pubmed/33791890
http://dx.doi.org/10.1186/s40634-021-00345-y
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