Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift

Diethyl malonate-based fluorescent probe NE-N(2)H(4) was constructed for monitoring hydrazine (N(2)H(4)). The novel probe NE-N(2)H(4) exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N(2)H(4) can be operated to detect...

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Detalles Bibliográficos
Autores principales: Qu, Jianbo, Zhang, Zhi-Hao, Zhang, Haitao, Weng, Zhen-Tao, Wang, Jian-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012553/
https://www.ncbi.nlm.nih.gov/pubmed/33816431
http://dx.doi.org/10.3389/fchem.2020.602125
Descripción
Sumario:Diethyl malonate-based fluorescent probe NE-N(2)H(4) was constructed for monitoring hydrazine (N(2)H(4)). The novel probe NE-N(2)H(4) exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N(2)H(4) can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N(2)H(4) might be used to monitor hydrazine in biosamples and environmental problem.

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