Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift

Diethyl malonate-based fluorescent probe NE-N(2)H(4) was constructed for monitoring hydrazine (N(2)H(4)). The novel probe NE-N(2)H(4) exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N(2)H(4) can be operated to detect...

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Autores principales: Qu, Jianbo, Zhang, Zhi-Hao, Zhang, Haitao, Weng, Zhen-Tao, Wang, Jian-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012553/
https://www.ncbi.nlm.nih.gov/pubmed/33816431
http://dx.doi.org/10.3389/fchem.2020.602125
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author Qu, Jianbo
Zhang, Zhi-Hao
Zhang, Haitao
Weng, Zhen-Tao
Wang, Jian-Yong
author_facet Qu, Jianbo
Zhang, Zhi-Hao
Zhang, Haitao
Weng, Zhen-Tao
Wang, Jian-Yong
author_sort Qu, Jianbo
collection PubMed
description Diethyl malonate-based fluorescent probe NE-N(2)H(4) was constructed for monitoring hydrazine (N(2)H(4)). The novel probe NE-N(2)H(4) exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N(2)H(4) can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N(2)H(4) might be used to monitor hydrazine in biosamples and environmental problem.
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spelling pubmed-80125532021-04-02 Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift Qu, Jianbo Zhang, Zhi-Hao Zhang, Haitao Weng, Zhen-Tao Wang, Jian-Yong Front Chem Chemistry Diethyl malonate-based fluorescent probe NE-N(2)H(4) was constructed for monitoring hydrazine (N(2)H(4)). The novel probe NE-N(2)H(4) exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N(2)H(4) can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N(2)H(4) might be used to monitor hydrazine in biosamples and environmental problem. Frontiers Media S.A. 2021-03-18 /pmc/articles/PMC8012553/ /pubmed/33816431 http://dx.doi.org/10.3389/fchem.2020.602125 Text en Copyright © 2021 Qu, Zhang, Zhang, Weng and Wang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Qu, Jianbo
Zhang, Zhi-Hao
Zhang, Haitao
Weng, Zhen-Tao
Wang, Jian-Yong
Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_full Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_fullStr Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_full_unstemmed Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_short Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_sort diethyl malonate-based turn-on chemical probe for detecting hydrazine and its bio-imaging and environmental applications with large stokes shift
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012553/
https://www.ncbi.nlm.nih.gov/pubmed/33816431
http://dx.doi.org/10.3389/fchem.2020.602125
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