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The RelA hydrolase domain acts as a molecular switch for (p)ppGpp synthesis

Bacteria synthesize guanosine tetra- and penta phosphate (commonly referred to as (p)ppGpp) in response to environmental stresses. (p)ppGpp reprograms cell physiology and is essential for stress survival, virulence and antibiotic tolerance. Proteins of the RSH superfamily (RelA/SpoT Homologues) are...

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Detalles Bibliográficos
Autores principales:	Sinha, Anurag Kumar, Winther, Kristoffer Skovbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012599/ https://www.ncbi.nlm.nih.gov/pubmed/33790389 http://dx.doi.org/10.1038/s42003-021-01963-z

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