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A continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex

A crucial role of cortical networks is the conversion of sensory inputs into perception. In the cortical somatosensory network, neurons of the primary somatosensory cortex (S1) show invariant sensory responses, while frontal lobe neuronal activity correlates with the animal’s perceptual behavior. He...

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Autores principales: Rossi-Pool, Román, Zainos, Antonio, Alvarez, Manuel, Diaz-deLeon, Gabriel, Romo, Ranulfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012659/
https://www.ncbi.nlm.nih.gov/pubmed/33790301
http://dx.doi.org/10.1038/s41467-021-22321-x
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author Rossi-Pool, Román
Zainos, Antonio
Alvarez, Manuel
Diaz-deLeon, Gabriel
Romo, Ranulfo
author_facet Rossi-Pool, Román
Zainos, Antonio
Alvarez, Manuel
Diaz-deLeon, Gabriel
Romo, Ranulfo
author_sort Rossi-Pool, Román
collection PubMed
description A crucial role of cortical networks is the conversion of sensory inputs into perception. In the cortical somatosensory network, neurons of the primary somatosensory cortex (S1) show invariant sensory responses, while frontal lobe neuronal activity correlates with the animal’s perceptual behavior. Here, we report that in the secondary somatosensory cortex (S2), neurons with invariant sensory responses coexist with neurons whose responses correlate with perceptual behavior. Importantly, the vast majority of the neurons fall along a continuum of combined sensory and categorical dynamics. Furthermore, during a non-demanding control task, the sensory responses remain unaltered while the sensory information exhibits an increase. However, perceptual responses and the associated categorical information decrease, implicating a task context-dependent processing mechanism. Conclusively, S2 neurons exhibit intriguing dynamics that are intermediate between those of S1 and frontal lobe. Our results contribute relevant evidence about the role that S2 plays in the conversion of touch into perception.
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spelling pubmed-80126592021-04-16 A continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex Rossi-Pool, Román Zainos, Antonio Alvarez, Manuel Diaz-deLeon, Gabriel Romo, Ranulfo Nat Commun Article A crucial role of cortical networks is the conversion of sensory inputs into perception. In the cortical somatosensory network, neurons of the primary somatosensory cortex (S1) show invariant sensory responses, while frontal lobe neuronal activity correlates with the animal’s perceptual behavior. Here, we report that in the secondary somatosensory cortex (S2), neurons with invariant sensory responses coexist with neurons whose responses correlate with perceptual behavior. Importantly, the vast majority of the neurons fall along a continuum of combined sensory and categorical dynamics. Furthermore, during a non-demanding control task, the sensory responses remain unaltered while the sensory information exhibits an increase. However, perceptual responses and the associated categorical information decrease, implicating a task context-dependent processing mechanism. Conclusively, S2 neurons exhibit intriguing dynamics that are intermediate between those of S1 and frontal lobe. Our results contribute relevant evidence about the role that S2 plays in the conversion of touch into perception. Nature Publishing Group UK 2021-03-31 /pmc/articles/PMC8012659/ /pubmed/33790301 http://dx.doi.org/10.1038/s41467-021-22321-x Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Rossi-Pool, Román
Zainos, Antonio
Alvarez, Manuel
Diaz-deLeon, Gabriel
Romo, Ranulfo
A continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex
title A continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex
title_full A continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex
title_fullStr A continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex
title_full_unstemmed A continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex
title_short A continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex
title_sort continuum of invariant sensory and behavioral-context perceptual coding in secondary somatosensory cortex
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012659/
https://www.ncbi.nlm.nih.gov/pubmed/33790301
http://dx.doi.org/10.1038/s41467-021-22321-x
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