Cargando…

TMPRSS4 Promotes Cell Proliferation and Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma by Activating ERK1/2 Signaling Pathway

Transmembrane protease serine 4 (TMPRSS4) is upregulated in various kinds of human cancers, including pancreatic cancer. However, its biological function in pancreatic ductal adenocarcinoma (PDAC) remains unclear. In the current study, real-time qPCR, immunohistochemical staining, Western blotting,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Jianyou, Huang, Wenjie, Zhang, Junfeng, Wang, Xianxing, Tao, Tian, Yang, Ludi, Zheng, Yao, Liu, Songsong, Yang, Jiali, Zhu, Liwei, Wang, Huaizhi, Fan, Yingfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012900/ https://www.ncbi.nlm.nih.gov/pubmed/33816264 http://dx.doi.org/10.3389/fonc.2021.628353

Ejemplares similares

MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation
por: Huang, Wenjie, et al.
Publicado: (2020)

The lncRNA RUNX1-IT1 regulates C-FOS transcription by interacting with RUNX1 in the process of pancreatic cancer proliferation, migration and invasion
por: Liu, Songsong, et al.
Publicado: (2020)

Alteration of tumor-associated macrophage subtypes mediated by KRT6A in pancreatic ductal adenocarcinoma
por: Zhang, Junfeng, et al.
Publicado: (2020)

Activating miRNA-mRNA network in gemcitabine-resistant pancreatic cancer cell associates with alteration of memory CD4(+) T cells
por: Gu, Jianyou, et al.
Publicado: (2020)

The m6A methyltransferase METTL16 inhibits the proliferation of pancreatic adenocarcinoma cancer cells via the p21 signaling pathway
por: Xie, Fuming, et al.
Publicado: (2023)

Corrigendum: The m6A methyltransferase METTL16 inhibits the proliferation of pancreatic adenocarcinoma cancer cells via the p21 signaling pathway
por: Xie, Fuming, et al.
Publicado: (2023)

Hsa-miR-3178/RhoB/PI3K/Akt, a novel signaling pathway regulates ABC transporters to reverse gemcitabine resistance in pancreatic cancer
por: Gu, Jianyou, et al.
Publicado: (2022)

Functional Significance and Therapeutic Potential of miR-15a Mimic in Pancreatic Ductal Adenocarcinoma
por: Guo, Shixiang, et al.
Publicado: (2019)

Lin28B facilitates the progression and metastasis of pancreatic ductal adenocarcinoma
por: Wang, Yunchao, et al.
Publicado: (2017)

Increased expression of miR-194-5p through the circPVRL3/miR-194-5p/SOCS2 axis promotes proliferation and metastasis in pancreatic ductal adenocarcinoma by activating the PI3K/AKT signaling pathway
por: Chi, Bojing, et al.
Publicado: (2022)

Establishing and validating a pathway prognostic signature in pancreatic cancer based on miRNA and mRNA sets using GSVA
por: Zhang, Junfeng, et al.
Publicado: (2020)

Upregulated GDF-15 expression facilitates pancreatic ductal adenocarcinoma progression through orphan receptor GFRAL
por: Zhao, Zhiping, et al.
Publicado: (2020)

Long-Term Effect of Pancreaticoduodenectomy Combined with Revascularization for Resectable Pancreatic Carcinoma in Elderly Patients
por: Yang, Jiali, et al.
Publicado: (2022)

SYPL1 Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma via Suppression of ROS-Induced ERK Activation
por: Song, Yunda, et al.
Publicado: (2020)

Methylation-mediated LINC00261 suppresses pancreatic cancer progression by epigenetically inhibiting c-Myc transcription
por: Liu, Songsong, et al.
Publicado: (2020)

CircPTPRA promotes the progression of pancreatic ductal adenocarcinoma via the miR‐140‐5p/LMNB1 axis
por: Fu, Wen, et al.
Publicado: (2023)

Tsoong induces apoptosis and inhibits proliferation, migration and invasion of pancreatic ductal adenocarcinoma cells
por: Luan, Yun-Peng, et al.
Publicado: (2018)

Effect of miR-184 on Proliferation and Apoptosis of Pancreatic Ductal Adenocarcinoma and Its Mechanism
por: Li, Shentao, et al.
Publicado: (2020)

TRPM2 promotes the proliferation and invasion of pancreatic ductal adenocarcinoma
por: Lin, Rui, et al.
Publicado: (2018)

Differential Effects of Dietary Macronutrients on the Development of Oncogenic KRAS-Mediated Pancreatic Ductal Adenocarcinoma
por: Zhu, Liang, et al.
Publicado: (2022)

Molecular markers associated with perineural invasion in pancreatic ductal adenocarcinoma
por: Zhang, Junfeng, et al.
Publicado: (2020)

MicroRNA-664 targets paired box protein 6 to inhibit the oncogenicity of pancreatic ductal adenocarcinoma
por: Wang, Qi, et al.
Publicado: (2022)

Laminin-332 mediates proliferation, apoptosis, invasion, migration and epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma
por: Huang, Caiqun, et al.
Publicado: (2021)

An Increased Abundance of Tumor-Infiltrating Regulatory T Cells Is Correlated with the Progression and Prognosis of Pancreatic Ductal Adenocarcinoma
por: Tang, Yichen, et al.
Publicado: (2014)

Microarray expression profile of circular RNAs in human pancreatic ductal adenocarcinoma
por: Qu, Shibin, et al.
Publicado: (2015)

Galectins Are Central Mediators of Immune Escape in Pancreatic Ductal Adenocarcinoma
por: Jiang, Zhengting, et al.
Publicado: (2022)

Mechanisms of drug resistance of pancreatic ductal adenocarcinoma at different levels
por: Du, Jiali, et al.
Publicado: (2020)

Targeting the prohibitin scaffold-CRAF kinase interaction in RAS-ERK-driven pancreatic ductal adenocarcinoma
por: Luan, Zhou, et al.
Publicado: (2014)

IL2RA is a prognostic indicator and correlated with immune characteristics of pancreatic ductal adenocarcinoma
por: Fan, Liwen, et al.
Publicado: (2022)

A Survival Model in Locally Advanced and Metastatic Pancreatic Ductal Adenocarcinoma
por: Wang, Yi, et al.
Publicado: (2018)

Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma
por: Zhang, Tianyi, et al.
Publicado: (2022)

CDCA8/SNAI2 Complex Activates CD44 to Promote Proliferation and Invasion of Pancreatic Ductal Adenocarcinoma
por: Gu, Jichun, et al.
Publicado: (2022)

SLPI knockdown induced pancreatic ductal adenocarcinoma cells proliferation and invasion
por: Zhang, Wei, et al.
Publicado: (2015)

Duodenum-preserving pancreatic head resection compared to pancreaticoduodenectomy: A systematic review and network meta-analysis of surgical outcomes
por: Guo, Shixiang, et al.
Publicado: (2023)

A novel prognostic factor TIPE2 inhibits cell proliferation and promotes apoptosis in pancreatic ductal adenocarcinoma (PDAC)
por: Sun, Yuqi, et al.
Publicado: (2021)

Circular RNA expression in pancreatic ductal adenocarcinoma
por: Zhang, Qian, et al.
Publicado: (2019)

The use of Multidimensional Data to Identify the Molecular Biomarker for Pancreatic Ductal Adenocarcinoma
por: Zhuang, Liwei, et al.
Publicado: (2013)

TBL1XR1 induces cell proliferation and inhibit cell apoptosis by the PI3K/AKT pathway in pancreatic ductal adenocarcinoma
por: Gu, Jian-Feng, et al.
Publicado: (2020)

FoxO1-negative cells are cancer stem-like cells in pancreatic ductal adenocarcinoma
por: Song, Weifeng, et al.
Publicado: (2015)

Metabolism remodeling in pancreatic ductal adenocarcinoma
por: Li, Jin-Tao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vse0p336f7ag5r98go13i06nnj