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Obesity as a driver of international differences in COVID‐19 death rates

AIM: To determine what proportion of the inter‐country variation in death rates can be explained in terms of obesity rates and other known risk factors for coronavirus disease 2019 (COVID‐19). MATERIALS AND METHODS: COVID‐19 death rates from 30 industrialized countries were analysed using linear reg...

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Detalles Bibliográficos
Autores principales: Gardiner, Julian, Oben, Jude, Sutcliffe, Alastair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013490/
https://www.ncbi.nlm.nih.gov/pubmed/33620765
http://dx.doi.org/10.1111/dom.14357
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author Gardiner, Julian
Oben, Jude
Sutcliffe, Alastair
author_facet Gardiner, Julian
Oben, Jude
Sutcliffe, Alastair
author_sort Gardiner, Julian
collection PubMed
description AIM: To determine what proportion of the inter‐country variation in death rates can be explained in terms of obesity rates and other known risk factors for coronavirus disease 2019 (COVID‐19). MATERIALS AND METHODS: COVID‐19 death rates from 30 industrialized countries were analysed using linear regression models. Covariates modelled population density, the age structure of the population, obesity, population health, per capita gross domestic product (GDP), ethnic diversity, national temperature and the delay in the government imposing virus control measures. RESULTS: The multivariable regression model explained 63% of the inter‐country variation in COVID‐19 death rates. The initial model was optimized using stepwise selection. In descending order of absolute size of model coefficient, the covariates in the optimized model were the obesity rate, the hypertension rate, population density, life expectancy, the percentage of the population aged older than 65 years, the percentage of the population aged younger than 15 years, the diabetes rate, the delay in imposing national COVID‐19 control measures, per capita GDP and mean temperature (with a negative coefficient indicating an association between higher national temperatures and lower death rates). CONCLUSIONS: A large proportion of the inter‐country variation in COVID‐19 death rates can be explained by differences in obesity rates, population health, population densities, age demographics, delays in imposing national virus control measures, per capita GDP and climate. Some of the unexplained variation is probably attributable to inter‐country differences in the definition of a COVID‐19 death and in the completeness of the recording of COVID‐19 deaths.
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spelling pubmed-80134902021-04-01 Obesity as a driver of international differences in COVID‐19 death rates Gardiner, Julian Oben, Jude Sutcliffe, Alastair Diabetes Obes Metab Original Articles AIM: To determine what proportion of the inter‐country variation in death rates can be explained in terms of obesity rates and other known risk factors for coronavirus disease 2019 (COVID‐19). MATERIALS AND METHODS: COVID‐19 death rates from 30 industrialized countries were analysed using linear regression models. Covariates modelled population density, the age structure of the population, obesity, population health, per capita gross domestic product (GDP), ethnic diversity, national temperature and the delay in the government imposing virus control measures. RESULTS: The multivariable regression model explained 63% of the inter‐country variation in COVID‐19 death rates. The initial model was optimized using stepwise selection. In descending order of absolute size of model coefficient, the covariates in the optimized model were the obesity rate, the hypertension rate, population density, life expectancy, the percentage of the population aged older than 65 years, the percentage of the population aged younger than 15 years, the diabetes rate, the delay in imposing national COVID‐19 control measures, per capita GDP and mean temperature (with a negative coefficient indicating an association between higher national temperatures and lower death rates). CONCLUSIONS: A large proportion of the inter‐country variation in COVID‐19 death rates can be explained by differences in obesity rates, population health, population densities, age demographics, delays in imposing national virus control measures, per capita GDP and climate. Some of the unexplained variation is probably attributable to inter‐country differences in the definition of a COVID‐19 death and in the completeness of the recording of COVID‐19 deaths. Blackwell Publishing Ltd 2021-03-15 2021-07 /pmc/articles/PMC8013490/ /pubmed/33620765 http://dx.doi.org/10.1111/dom.14357 Text en © 2021 University College London. Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Gardiner, Julian
Oben, Jude
Sutcliffe, Alastair
Obesity as a driver of international differences in COVID‐19 death rates
title Obesity as a driver of international differences in COVID‐19 death rates
title_full Obesity as a driver of international differences in COVID‐19 death rates
title_fullStr Obesity as a driver of international differences in COVID‐19 death rates
title_full_unstemmed Obesity as a driver of international differences in COVID‐19 death rates
title_short Obesity as a driver of international differences in COVID‐19 death rates
title_sort obesity as a driver of international differences in covid‐19 death rates
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013490/
https://www.ncbi.nlm.nih.gov/pubmed/33620765
http://dx.doi.org/10.1111/dom.14357
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