Cargando…

GAD antibody-spectrum disorders: progress in clinical phenotypes, immunopathogenesis and therapeutic interventions

Antibodies against glutamic acid decarboxylase (GAD), originally linked to stiff person syndrome (SPS), now denote the “GAD antibody-spectrum disorders” (GAD-SD) that also include autoimmune epilepsy, limbic encephalitis, cerebellar ataxia and nystagmus with overlapping symptomatology highlighting a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsiortou, Popianna, Alexopoulos, Harry, Dalakas, Marinos C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Autoimmune Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8013924/ https://www.ncbi.nlm.nih.gov/pubmed/33854562 http://dx.doi.org/10.1177/17562864211003486

Ejemplares similares

Stiff-person Syndrome and GAD Antibody-spectrum Disorders: GABAergic Neuronal Excitability, Immunopathogenesis and Update on Antibody Therapies
por: Dalakas, Marinos C.
Publicado: (2022)

Short segment myelitis as the initial and only manifestation of aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorders
por: Fang*, Wei, et al.
Publicado: (2020)

Advances in the diagnosis, immunopathogenesis and therapies of IgM-anti-MAG antibody-mediated neuropathies
por: Dalakas, Marinos C.
Publicado: (2018)

Autoimmune encephalopathies presenting as dementia of subacute onset and rapid progression
por: Banks, Samantha A., et al.
Publicado: (2021)

C3, C5a and anti-acetylcholine receptor antibody as severity biomarkers in myasthenia gravis
por: Aguirre, Florencia, et al.
Publicado: (2020)

Possible coexistence of MOG-IgG-associated disease and anti-Caspr2 antibody-associated autoimmune encephalitis: a first case report
por: Liu, Pei, et al.
Publicado: (2020)

Post-infectious neurological disorders
por: Blackburn, Kyle M., et al.
Publicado: (2020)

Recognising the spectrum of scleromyositis: HEp-2 ANA patterns allow identification of a novel clinical subset with anti-SMN autoantibodies
por: Landon-Cardinal, Océane, et al.
Publicado: (2020)

Recent developments in MOG-IgG associated neurological disorders
por: Hegen, Harald, et al.
Publicado: (2020)

Machine Learning for the Identification of a Common Signature for Anti–SSA/Ro 60 Antibody Expression Across Autoimmune Diseases
por: Foulquier, Nathan, et al.
Publicado: (2022)

Long-term Effectiveness of IVIg Maintenance Therapy in 36 Patients With GAD Antibody–Positive Stiff-Person Syndrome
por: Yi, Jessica, et al.
Publicado: (2022)

Pathophysiology of paraneoplastic and autoimmune encephalitis: genes, infections, and checkpoint inhibitors
por: Vogrig, Alberto, et al.
Publicado: (2020)

Vision improvement in severe acute isolated optic neuritis after plasma exchange treatment in Chinese population: a prospective case series study
por: Tan, Shaoying, et al.
Publicado: (2020)

Application of the 2017 McDonald criteria in a Chinese population with clinically isolated syndrome
por: Zheng*, Yang, et al.
Publicado: (2020)

Suitable indications of eculizumab for patients with refractory generalized myasthenia gravis
por: Oyama, Munenori, et al.
Publicado: (2020)

Inflammation in multiple sclerosis
por: Haase, Stefanie, et al.
Publicado: (2021)

Paraneoplastic neurological syndromes: clinical presentations and management
por: Devine, Michelle F., et al.
Publicado: (2021)

Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia
por: Disserol, Caio César Diniz, et al.
Publicado: (2023)

Diagnostic markers and potential therapeutic agents for Sjögren’s syndrome screened through multiple machine learning and molecular docking
por: Zhou, Liqing, et al.
Publicado: (2023)

A novel monoclonal antibody with improved FcγR blocking ability demonstrated non-inferior efficacy compared to IVIG in cynomolgus monkey ITP model at considerably lower dose
por: Nakajima-Kato, Yuko, et al.
Publicado: (2022)

CTLA4, SH2B3, and CLEC16A diversely affect the progression of early islet autoimmunity in relatives of Type 1 diabetes patients
por: Vandewalle, Julie, et al.
Publicado: (2023)

Anti-SARS-CoV-2 Antibodies Within IVIg Preparations: Cross-Reactivities With Seasonal Coronaviruses, Natural Autoimmunity, and Therapeutic Implications
por: Dalakas, Marinos C., et al.
Publicado: (2021)

The longitudinal loss of islet autoantibody responses from diagnosis of type 1 diabetes occurs progressively over follow-up and is determined by low autoantibody titres, early-onset, and genetic variants
por: Williams, C L, et al.
Publicado: (2022)

Complement in neurological disorders and emerging complement-targeted therapeutics
por: Dalakas, Marinos C., et al.
Publicado: (2020)

Quantitative clinical and autoimmune assessments in stiff person syndrome: evidence for a progressive disorder
por: Rakocevic, Goran, et al.
Publicado: (2019)

Functional Analysis of a Complement Polymorphism (rs17611) Associated with Rheumatoid Arthritis
por: Giles, Joanna L., et al.
Publicado: (2015)

Cancer immunotherapy-induced rheumatic diseases emerge as new clinical entities
por: Cappelli, Laura C, et al.
Publicado: (2016)

Suppression of IRAK1 or IRAK4 Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding–Defective Mutant of ABIN1
por: Nanda, Sambit K., et al.
Publicado: (2016)

Tissue-Resident Exhausted Effector Memory CD8(+) T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis
por: Boldison, Joanne, et al.
Publicado: (2014)

Characteristics and treatment of new-onset arthritis after checkpoint inhibitor therapy
por: Leipe, Jan, et al.
Publicado: (2018)

Distinct features distinguishing IgG4-related disease from multicentric Castleman’s disease
por: Sasaki, Takanori, et al.
Publicado: (2017)

The Lupus‐Associated Fcγ Receptor IIb–I232T Polymorphism Results in Impairment in the Negative Selection of Low‐Affinity Germinal Center B Cells Via c‐Abl in Mice
por: Jhou, Jyun‐Pei, et al.
Publicado: (2018)

Antiphospholipid syndrome: state of the art on clinical practice guidelines
por: Limper, Marteen, et al.
Publicado: (2018)

Automated evaluation of ANA under real-life conditions
por: Loock, Clemens Dario, et al.
Publicado: (2017)

Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity
por: Roberts, Natalie A., et al.
Publicado: (2017)

Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice
por: Sood, Shatakshi, et al.
Publicado: (2016)

Tbet or Continued RORγt Expression Is Not Required for Th17-Associated Immunopathology
por: Brucklacher-Waldert, Verena, et al.
Publicado: (2016)

Rheumatic immune-related adverse events of checkpoint therapy for cancer: case series of a new nosological entity
por: Calabrese, C, et al.
Publicado: (2017)

Systemic Autoimmune Disease Among Adults Exposed to the September 11, 2001 Terrorist Attack
por: Miller‐Archie, Sara A., et al.
Publicado: (2020)

Efficacy, immunogenicity and safety of vaccination in adult patients with autoimmune inflammatory rheumatic diseases: a systematic literature review for the 2019 update of EULAR recommendations
por: Rondaan, Christien, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cd6dv8lfeiecadnl63onhqaqjf