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Responsive Plasmonic Nanomaterials for Advanced Cancer Diagnostics
Plasmonic nanostructures, particularly of noble-metal Au and Ag, have attracted long-lasting research interests because of their intriguing physical and chemical properties. Under light excitation, their conduction electrons can form collective oscillation with the electromagnetic fields at particul...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014002/ https://www.ncbi.nlm.nih.gov/pubmed/33816441 http://dx.doi.org/10.3389/fchem.2021.652287 |
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author | Lu, Rong Ni, Jiankun Yin, Shengnan Ji, Yiding |
author_facet | Lu, Rong Ni, Jiankun Yin, Shengnan Ji, Yiding |
author_sort | Lu, Rong |
collection | PubMed |
description | Plasmonic nanostructures, particularly of noble-metal Au and Ag, have attracted long-lasting research interests because of their intriguing physical and chemical properties. Under light excitation, their conduction electrons can form collective oscillation with the electromagnetic fields at particular wavelength, leading to localized surface plasmon resonance (LSPR). The remarkable characteristic of LSPR is the absorption and scattering of light at the resonant wavelength and greatly enhanced electric fields in localized areas. In response to the chemical and physical changes, these optical properties of plasmonic nanostructures will exhibit drastic color changes and highly sensitive peak shifts, which has been extensively used for biological imaging and disease treatments. In this mini review, we aim to briefly summarize recent progress of preparing responsive plasmonic nanostructures for biodiagnostics, with specific focus on cancer imaging and treatment. We start with typical synthetic approaches to various plasmonic nanostructures and elucidate practical strategies and working mechanism in tuning their LSPR properties. Current achievements in using responsive plasmonic nanostructures for advanced cancer diagnostics will be further discussed. Concise perspectives on existing challenges in developing plasmonic platforms for clinic diagnostics is also provided at the end of this review. |
format | Online Article Text |
id | pubmed-8014002 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-80140022021-04-02 Responsive Plasmonic Nanomaterials for Advanced Cancer Diagnostics Lu, Rong Ni, Jiankun Yin, Shengnan Ji, Yiding Front Chem Chemistry Plasmonic nanostructures, particularly of noble-metal Au and Ag, have attracted long-lasting research interests because of their intriguing physical and chemical properties. Under light excitation, their conduction electrons can form collective oscillation with the electromagnetic fields at particular wavelength, leading to localized surface plasmon resonance (LSPR). The remarkable characteristic of LSPR is the absorption and scattering of light at the resonant wavelength and greatly enhanced electric fields in localized areas. In response to the chemical and physical changes, these optical properties of plasmonic nanostructures will exhibit drastic color changes and highly sensitive peak shifts, which has been extensively used for biological imaging and disease treatments. In this mini review, we aim to briefly summarize recent progress of preparing responsive plasmonic nanostructures for biodiagnostics, with specific focus on cancer imaging and treatment. We start with typical synthetic approaches to various plasmonic nanostructures and elucidate practical strategies and working mechanism in tuning their LSPR properties. Current achievements in using responsive plasmonic nanostructures for advanced cancer diagnostics will be further discussed. Concise perspectives on existing challenges in developing plasmonic platforms for clinic diagnostics is also provided at the end of this review. Frontiers Media S.A. 2021-03-18 /pmc/articles/PMC8014002/ /pubmed/33816441 http://dx.doi.org/10.3389/fchem.2021.652287 Text en Copyright © 2021 Lu, Ni, Yin and Ji. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Chemistry Lu, Rong Ni, Jiankun Yin, Shengnan Ji, Yiding Responsive Plasmonic Nanomaterials for Advanced Cancer Diagnostics |
title | Responsive Plasmonic Nanomaterials for Advanced Cancer Diagnostics |
title_full | Responsive Plasmonic Nanomaterials for Advanced Cancer Diagnostics |
title_fullStr | Responsive Plasmonic Nanomaterials for Advanced Cancer Diagnostics |
title_full_unstemmed | Responsive Plasmonic Nanomaterials for Advanced Cancer Diagnostics |
title_short | Responsive Plasmonic Nanomaterials for Advanced Cancer Diagnostics |
title_sort | responsive plasmonic nanomaterials for advanced cancer diagnostics |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014002/ https://www.ncbi.nlm.nih.gov/pubmed/33816441 http://dx.doi.org/10.3389/fchem.2021.652287 |
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