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Production of high‐quality SARS‐CoV‐2 antigens: Impact of bioprocess and storage on glycosylation, biophysical attributes, and ELISA serologic tests performance

Serological assays are valuable tools to study SARS‐CoV‐2 spread and, importantly, to identify individuals that were already infected and would be potentially immune to a virus reinfection. SARS‐CoV‐2 Spike protein and its receptor binding domain (RBD) are the antigens with higher potential to devel...

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Detalles Bibliográficos
Autores principales: Castro, Rute, Nobre, Lígia S., Eleutério, Rute P., Thomaz, Mónica, Pires, António, Monteiro, Sandra M., Mendes, Sónia, Gomes, Ricardo A., Clemente, João J., Sousa, Marcos F. Q., Pinto, Filipe, Silva, Ana C., Freitas, Micael C., Lemos, Ana R., Akpogheneta, Onome, Kosack, Lindsay, Bergman, Marie‐Louise, Duarte, Nadia, Matoso, Paula, Costa, Júlia, Bandeiras, Tiago M., Gomes‐Alves, Patricia, Gonçalves, Carlos P., Demengeot, Jocelyne, Alves, Paula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014509/
https://www.ncbi.nlm.nih.gov/pubmed/33624859
http://dx.doi.org/10.1002/bit.27725

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