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Traumatic injury is associated with reduced deoxyribonuclease activity and dysregulation of the actin scavenging system

BACKGROUND: Traumatic injury is associated with increased concentrations of cell-free DNA (cfDNA) in the circulation, which contribute to post-injury complications. The endonuclease deoxyribonuclease 1 (DNase-1) is responsible for removing 90% of circulating cfDNA. Recently, DNase activity was repor...

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Detalles Bibliográficos
Autores principales:	Hazeldine, Jon, Dinsdale, Robert J, Naumann, David N, Acharjee, Animesh, Bishop, Jonathan R B, Lord, Janet M, Harrison, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014516/ https://www.ncbi.nlm.nih.gov/pubmed/33834079 http://dx.doi.org/10.1093/burnst/tkab001

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