Sex‐based differences in severity and mortality in COVID‐19

The current coronavirus disease (COVID‐19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS‐CoV and MERS‐CoV, and viral infections in general. Here, we...

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Detalles Bibliográficos
Autores principales: Alwani, Mustafa, Yassin, Aksam, Al‐Zoubi, Raed M., Aboumarzouk, Omar M., Nettleship, Joanne, Kelly, Daniel, AL‐Qudimat, Ahmad R., Shabsigh, Ridwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014761/
https://www.ncbi.nlm.nih.gov/pubmed/33646622
http://dx.doi.org/10.1002/rmv.2223
Descripción
Sumario:The current coronavirus disease (COVID‐19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS‐CoV and MERS‐CoV, and viral infections in general. Here, we discuss the sex‐disaggregated epidemiological data for COVID‐19 and highlight underlying differences that may explain the sexual dimorphism to help inform risk stratification strategies and therapeutic options.

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