Sex‐based differences in severity and mortality in COVID‐19

The current coronavirus disease (COVID‐19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS‐CoV and MERS‐CoV, and viral infections in general. Here, we...

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Autores principales: Alwani, Mustafa, Yassin, Aksam, Al‐Zoubi, Raed M., Aboumarzouk, Omar M., Nettleship, Joanne, Kelly, Daniel, AL‐Qudimat, Ahmad R., Shabsigh, Ridwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014761/
https://www.ncbi.nlm.nih.gov/pubmed/33646622
http://dx.doi.org/10.1002/rmv.2223
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author Alwani, Mustafa
Yassin, Aksam
Al‐Zoubi, Raed M.
Aboumarzouk, Omar M.
Nettleship, Joanne
Kelly, Daniel
AL‐Qudimat, Ahmad R.
Shabsigh, Ridwan
author_facet Alwani, Mustafa
Yassin, Aksam
Al‐Zoubi, Raed M.
Aboumarzouk, Omar M.
Nettleship, Joanne
Kelly, Daniel
AL‐Qudimat, Ahmad R.
Shabsigh, Ridwan
author_sort Alwani, Mustafa
collection PubMed
description The current coronavirus disease (COVID‐19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS‐CoV and MERS‐CoV, and viral infections in general. Here, we discuss the sex‐disaggregated epidemiological data for COVID‐19 and highlight underlying differences that may explain the sexual dimorphism to help inform risk stratification strategies and therapeutic options.
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spelling pubmed-80147612021-04-01 Sex‐based differences in severity and mortality in COVID‐19 Alwani, Mustafa Yassin, Aksam Al‐Zoubi, Raed M. Aboumarzouk, Omar M. Nettleship, Joanne Kelly, Daniel AL‐Qudimat, Ahmad R. Shabsigh, Ridwan Rev Med Virol Review The current coronavirus disease (COVID‐19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS‐CoV and MERS‐CoV, and viral infections in general. Here, we discuss the sex‐disaggregated epidemiological data for COVID‐19 and highlight underlying differences that may explain the sexual dimorphism to help inform risk stratification strategies and therapeutic options. John Wiley and Sons Inc. 2021-03-01 2021-11 /pmc/articles/PMC8014761/ /pubmed/33646622 http://dx.doi.org/10.1002/rmv.2223 Text en © 2021 The Authors. Reviews in Medical Virology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Alwani, Mustafa
Yassin, Aksam
Al‐Zoubi, Raed M.
Aboumarzouk, Omar M.
Nettleship, Joanne
Kelly, Daniel
AL‐Qudimat, Ahmad R.
Shabsigh, Ridwan
Sex‐based differences in severity and mortality in COVID‐19
title Sex‐based differences in severity and mortality in COVID‐19
title_full Sex‐based differences in severity and mortality in COVID‐19
title_fullStr Sex‐based differences in severity and mortality in COVID‐19
title_full_unstemmed Sex‐based differences in severity and mortality in COVID‐19
title_short Sex‐based differences in severity and mortality in COVID‐19
title_sort sex‐based differences in severity and mortality in covid‐19
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014761/
https://www.ncbi.nlm.nih.gov/pubmed/33646622
http://dx.doi.org/10.1002/rmv.2223
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