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COVID‐19 and cardiovascular problems in elderly patients: Food for thought

The global number of COVID‐19 infections, as of December 23, 2020, stood at approximately 79 million, with over 1.7 million deaths. The development of vascular inflammation may also contribute to a hypercoagulable state and endothelial dysfunction in such patients. It is known that multi‐organ damag...

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Detalles Bibliográficos
Autores principales: Costa, Raffaele, Castagna, Alberto, Ruotolo, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014783/
https://www.ncbi.nlm.nih.gov/pubmed/33821229
http://dx.doi.org/10.1002/agm2.12149
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author Costa, Raffaele
Castagna, Alberto
Ruotolo, Giovanni
author_facet Costa, Raffaele
Castagna, Alberto
Ruotolo, Giovanni
author_sort Costa, Raffaele
collection PubMed
description The global number of COVID‐19 infections, as of December 23, 2020, stood at approximately 79 million, with over 1.7 million deaths. The development of vascular inflammation may also contribute to a hypercoagulable state and endothelial dysfunction in such patients. It is known that multi‐organ damage is more likely in patients with sepsis if they develop coagulopathy and that inhibition of thrombin synthesis can have a positive impact in reducing mortality. In this review, we will focus on the protection of the most fragile groups of the population, such as the elderly. This segment of the population will be a key issue and probably of primary interest to all. Biomarkers appear to be extremely useful as an indicator of what is happening from a pathophysiological point of view in the heart, allowing us to better stratify the prognosis of our patients affected by COVID‐19, especially in the most severe cases and those with comorbidities.
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spelling pubmed-80147832021-04-01 COVID‐19 and cardiovascular problems in elderly patients: Food for thought Costa, Raffaele Castagna, Alberto Ruotolo, Giovanni Aging Med (Milton) Review Articles The global number of COVID‐19 infections, as of December 23, 2020, stood at approximately 79 million, with over 1.7 million deaths. The development of vascular inflammation may also contribute to a hypercoagulable state and endothelial dysfunction in such patients. It is known that multi‐organ damage is more likely in patients with sepsis if they develop coagulopathy and that inhibition of thrombin synthesis can have a positive impact in reducing mortality. In this review, we will focus on the protection of the most fragile groups of the population, such as the elderly. This segment of the population will be a key issue and probably of primary interest to all. Biomarkers appear to be extremely useful as an indicator of what is happening from a pathophysiological point of view in the heart, allowing us to better stratify the prognosis of our patients affected by COVID‐19, especially in the most severe cases and those with comorbidities. John Wiley and Sons Inc. 2021-02-28 /pmc/articles/PMC8014783/ /pubmed/33821229 http://dx.doi.org/10.1002/agm2.12149 Text en © 2021 The Authors. Aging Medicine published by Beijing Hospital and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Review Articles
Costa, Raffaele
Castagna, Alberto
Ruotolo, Giovanni
COVID‐19 and cardiovascular problems in elderly patients: Food for thought
title COVID‐19 and cardiovascular problems in elderly patients: Food for thought
title_full COVID‐19 and cardiovascular problems in elderly patients: Food for thought
title_fullStr COVID‐19 and cardiovascular problems in elderly patients: Food for thought
title_full_unstemmed COVID‐19 and cardiovascular problems in elderly patients: Food for thought
title_short COVID‐19 and cardiovascular problems in elderly patients: Food for thought
title_sort covid‐19 and cardiovascular problems in elderly patients: food for thought
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014783/
https://www.ncbi.nlm.nih.gov/pubmed/33821229
http://dx.doi.org/10.1002/agm2.12149
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