Dissolution Kinetics of a BCS Class II Active Pharmaceutical Ingredient: Diffusion-Based Model Validation and Prediction

[Image: see text] In this work, a diffusion-theory-based model has been devised to simulate dissolution kinetics of a poorly water-soluble drug, ibuprofen. The model was developed from the Noyes–Whitney equation in which the dissolution rate term is a function of the remaining particulate surface ar...

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Detalles Bibliográficos
Autores principales: Gao, Yuan, Glennon, Brian, He, Yunliang, Donnellan, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014923/
https://www.ncbi.nlm.nih.gov/pubmed/33817465
http://dx.doi.org/10.1021/acsomega.0c05558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014923/
https://www.ncbi.nlm.nih.gov/pubmed/33817465
http://dx.doi.org/10.1021/acsomega.0c05558

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