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Dissolution Kinetics of a BCS Class II Active Pharmaceutical Ingredient: Diffusion-Based Model Validation and Prediction
[Image: see text] In this work, a diffusion-theory-based model has been devised to simulate dissolution kinetics of a poorly water-soluble drug, ibuprofen. The model was developed from the Noyes–Whitney equation in which the dissolution rate term is a function of the remaining particulate surface ar...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014923/ https://www.ncbi.nlm.nih.gov/pubmed/33817465 http://dx.doi.org/10.1021/acsomega.0c05558 |