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PI3K/AKT/mTOR signalling pathway involvement in renal cell carcinoma pathogenesis (Review)

Renal cell carcinoma (RCC) accounts for over 90% of all renal malignancies, and mainly affects the male population. Obesity and smoking are involved in the pathogenesis of several systemic cancers including RCC. The phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamyci...

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Detalles Bibliográficos
Autores principales: Miricescu, Daniela, Balan, Daniela Gabriela, Tulin, Adrian, Stiru, Ovidiu, Vacaroiu, Ileana Adela, Mihai, Doina Andrada, Popa, Cristian Constantin, Papacocea, Raluca Ioana, Enyedi, Mihaly, Sorin, Nedelea Andrei, Vatachki, Guenadiy, Georgescu, Dragoș Eugen, Nica, Adriana Elena, Stefani, Constantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014975/
https://www.ncbi.nlm.nih.gov/pubmed/33815613
http://dx.doi.org/10.3892/etm.2021.9972