Focus on Human Monoamine Transporter Selectivity. New Human DAT and NET Models, Experimental Validation, and SERT Affinity Exploration

[Image: see text] The most commonly used antidepressant drugs are the serotonin transporter inhibitors. Their effects depend strongly on the selectivity for a single monoamine transporter compared to other amine transporters or receptors, and the selectivity is roughly influenced by the spatial prot...

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Detalles Bibliográficos
Autores principales: Ortore, Gabriella, Orlandini, Elisabetta, Betti, Laura, Giannaccini, Gino, Mazzoni, Maria Rosa, Camodeca, Caterina, Nencetti, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015229/
https://www.ncbi.nlm.nih.gov/pubmed/32991141
http://dx.doi.org/10.1021/acschemneuro.0c00304

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