A novel LC-MS/MS method for determination of the potential antiviral candidate favipiravir for the emergency treatment of SARS-CoV-2 virus in human plasma: Application to a bioequivalence study in Egyptian human volunteers

A novel, fast and sensitive LC–MS/MS method was developed and validated for the bioanalysis of the antiviral agent favipiravir (FAV); a promising candidate for treatment of SARS-CoV-2 (COVID-19) in human plasma using pyrazinamide as an internal standard (IS). Simple protein precipitation was adopted...

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Detalles Bibliográficos
Autores principales: Morsy, Mosaad I., Nouman, Eman G., Abdallah, Youmna M., Zainelabdeen, Mourd A., Darwish, Mohamed M., Hassan, Ahmed Y., Gouda, Amira S., Rezk, Mamdouh R., Abdel-Megied, Ahmed M., Marzouk, Hoda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015396/
https://www.ncbi.nlm.nih.gov/pubmed/33831737
http://dx.doi.org/10.1016/j.jpba.2021.114057

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