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Clinical Presentation and outcome of acute disseminated encephalomyelitis in Saudi Arabia: Tertiary Center Experience
OBJECTIVES: To evaluate the clinical presenation of acute disseminated Encephalomyelitis (ADEM) in pediatric age group, treatments, and to asses the outcome at King Abdulaziz Medical City, Riyadh, Kingdom of Saudia Arabia. METHODS: The medical records of all patients younger than 18 years of age wit...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Riyadh : Armed Forces Hospital
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015459/ https://www.ncbi.nlm.nih.gov/pubmed/31056539 http://dx.doi.org/10.17712/nsj.2019.2.20180017 |
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author | Aldamkh, Bander Ali Alamer, Abdalaziz F. Altuwaijri, Mohammed M. Alrumayyan, Mohammed A. Alhaqbani, Abdulaziz H. Alharthi, Nawaf A. Aldamkh, Saeed A. Aldrees, Amjad S. Alrifai, Muhammad T. Altuwaijri, Waleed Alrumayyan, Ahmed |
author_facet | Aldamkh, Bander Ali Alamer, Abdalaziz F. Altuwaijri, Mohammed M. Alrumayyan, Mohammed A. Alhaqbani, Abdulaziz H. Alharthi, Nawaf A. Aldamkh, Saeed A. Aldrees, Amjad S. Alrifai, Muhammad T. Altuwaijri, Waleed Alrumayyan, Ahmed |
author_sort | Aldamkh, Bander Ali |
collection | PubMed |
description | OBJECTIVES: To evaluate the clinical presenation of acute disseminated Encephalomyelitis (ADEM) in pediatric age group, treatments, and to asses the outcome at King Abdulaziz Medical City, Riyadh, Kingdom of Saudia Arabia. METHODS: The medical records of all patients younger than 18 years of age with a diagnosis of ADEM and treated at King Abdulaziz Medical City from January 1996 to Decemeber 2016 were collected. A total of 20 patients were included. RESULTS: Of 20 patients enrolled in our study, 13 (65%) were female. Autumn and summer were the most common seasons in which ADEM presented (60%); 19 (95%) patients had a history of preceding viral illnesses. The most common neurological deficits on presentation were weakness (85%), ataxia (45%), and nystagmus (45%). Cortical and subcortical lesions (60%) were the most common finding on cranial magnetic resonance imaging. Seventeen patients (85%) received steroid only. Only 16 patients continued with follow-up, with a mean duration of 7 months. All 16 patients improved: 11 patients were recovered and 5 patients still had a neurological deficit at the clinic visits. No patient had relapsed. CONCLUSION: Most of the patients in this case series have an excellent outcome and attended follow-up visits and no disease relapses were identified. Further exploration of the disease is recommended. |
format | Online Article Text |
id | pubmed-8015459 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Riyadh : Armed Forces Hospital |
record_format | MEDLINE/PubMed |
spelling | pubmed-80154592021-08-13 Clinical Presentation and outcome of acute disseminated encephalomyelitis in Saudi Arabia: Tertiary Center Experience Aldamkh, Bander Ali Alamer, Abdalaziz F. Altuwaijri, Mohammed M. Alrumayyan, Mohammed A. Alhaqbani, Abdulaziz H. Alharthi, Nawaf A. Aldamkh, Saeed A. Aldrees, Amjad S. Alrifai, Muhammad T. Altuwaijri, Waleed Alrumayyan, Ahmed Neurosciences (Riyadh) Original Article OBJECTIVES: To evaluate the clinical presenation of acute disseminated Encephalomyelitis (ADEM) in pediatric age group, treatments, and to asses the outcome at King Abdulaziz Medical City, Riyadh, Kingdom of Saudia Arabia. METHODS: The medical records of all patients younger than 18 years of age with a diagnosis of ADEM and treated at King Abdulaziz Medical City from January 1996 to Decemeber 2016 were collected. A total of 20 patients were included. RESULTS: Of 20 patients enrolled in our study, 13 (65%) were female. Autumn and summer were the most common seasons in which ADEM presented (60%); 19 (95%) patients had a history of preceding viral illnesses. The most common neurological deficits on presentation were weakness (85%), ataxia (45%), and nystagmus (45%). Cortical and subcortical lesions (60%) were the most common finding on cranial magnetic resonance imaging. Seventeen patients (85%) received steroid only. Only 16 patients continued with follow-up, with a mean duration of 7 months. All 16 patients improved: 11 patients were recovered and 5 patients still had a neurological deficit at the clinic visits. No patient had relapsed. CONCLUSION: Most of the patients in this case series have an excellent outcome and attended follow-up visits and no disease relapses were identified. Further exploration of the disease is recommended. Riyadh : Armed Forces Hospital 2019-04 /pmc/articles/PMC8015459/ /pubmed/31056539 http://dx.doi.org/10.17712/nsj.2019.2.20180017 Text en Copyright: © Neurosciences https://creativecommons.org/licenses/by-nc-sa/3.0/Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. |
spellingShingle | Original Article Aldamkh, Bander Ali Alamer, Abdalaziz F. Altuwaijri, Mohammed M. Alrumayyan, Mohammed A. Alhaqbani, Abdulaziz H. Alharthi, Nawaf A. Aldamkh, Saeed A. Aldrees, Amjad S. Alrifai, Muhammad T. Altuwaijri, Waleed Alrumayyan, Ahmed Clinical Presentation and outcome of acute disseminated encephalomyelitis in Saudi Arabia: Tertiary Center Experience |
title | Clinical Presentation and outcome of acute disseminated encephalomyelitis in Saudi Arabia: Tertiary Center Experience |
title_full | Clinical Presentation and outcome of acute disseminated encephalomyelitis in Saudi Arabia: Tertiary Center Experience |
title_fullStr | Clinical Presentation and outcome of acute disseminated encephalomyelitis in Saudi Arabia: Tertiary Center Experience |
title_full_unstemmed | Clinical Presentation and outcome of acute disseminated encephalomyelitis in Saudi Arabia: Tertiary Center Experience |
title_short | Clinical Presentation and outcome of acute disseminated encephalomyelitis in Saudi Arabia: Tertiary Center Experience |
title_sort | clinical presentation and outcome of acute disseminated encephalomyelitis in saudi arabia: tertiary center experience |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015459/ https://www.ncbi.nlm.nih.gov/pubmed/31056539 http://dx.doi.org/10.17712/nsj.2019.2.20180017 |
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