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Fine-tuning p53 activity by modulating the interaction between eukaryotic translation initiation factor eIF4E and RNA-binding protein RBM38

p53 is critical for tumor suppression but also elicits detrimental effects when aberrantly overexpressed. Thus, multiple regulators, including RNA-binding protein RBM38, are found to tightly control p53 expression. Interestingly, RBM38 is unique in that it can either suppress or enhance p53 mRNA tra...

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Detalles Bibliográficos
Autores principales:	Sun, Wenqiang, Laubach, Kyra, Lucchessi, Christopher, Zhang, Yanhong, Chen, Mingyi, Zhang, Jin, Chen, Xinbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015715/ https://www.ncbi.nlm.nih.gov/pubmed/33664057 http://dx.doi.org/10.1101/gad.346148.120

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