WWTR1(TAZ)-CAMTA1 reprograms endothelial cells to drive epithelioid hemangioendothelioma

Epithelioid hemangioendothelioma (EHE) is a poorly understood and devastating vascular cancer. Sequencing of EHE has revealed a unique gene fusion between the Hippo pathway nuclear effector TAZ (WWTR1) and the brain-enriched transcription factor CAMTA1 in ∼90% of cases. However, it remains unclear w...

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Detalles Bibliográficos
Autores principales: Driskill, Jordan H., Zheng, Yonggang, Wu, Bo-Kuan, Wang, Li, Cai, Jing, Rakheja, Dinesh, Dellinger, Michael, Pan, Duojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015719/
https://www.ncbi.nlm.nih.gov/pubmed/33766984
http://dx.doi.org/10.1101/gad.348221.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015719/
https://www.ncbi.nlm.nih.gov/pubmed/33766984
http://dx.doi.org/10.1101/gad.348221.120

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