Cargando…
A flexible repertoire of transcription factor binding sites and a diversity threshold determines enhancer activity in embryonic stem cells
Transcriptional enhancers are critical for development and phenotype evolution and are often mutated in disease contexts; however, even in well-studied cell types, the sequence code conferring enhancer activity remains unknown. To examine the enhancer regulatory code for pluripotent stem cells, we i...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015845/ https://www.ncbi.nlm.nih.gov/pubmed/33712417 http://dx.doi.org/10.1101/gr.272468.120 |