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Complement C3a and C5a receptor blockade modulates regulatory T cell conversion in head and neck cancer

BACKGROUND: Resistance to therapy is a major problem in treating head and neck squamous cell carcinomas (HNSCC). Complement system inhibition has been shown to reduce tumor growth, metastasis, and therapeutic resistance in other tumor models, but has yet to be explored in the context of HNSCC. Here,...

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Detalles Bibliográficos
Autores principales:	Gadwa, Jacob, Bickett, Thomas E, Darragh, Laurel B, Knitz, Michael William, Bhatia, Shilpa, Piper, Miles, Van Court, Benjamin, Bhuvane, Shiv, Nguyen, Diemmy, Nangia, Varuna, Kleczko, Emily K, Nemenoff, Raphael A, Karam, Sana D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Clinical/Translational Cancer Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016081/ https://www.ncbi.nlm.nih.gov/pubmed/33789881 http://dx.doi.org/10.1136/jitc-2021-002585

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