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Computational epitope map of SARS-CoV-2 spike protein

The primary immunological target of COVID-19 vaccines is the SARS-CoV-2 spike (S) protein. S is exposed on the viral surface and mediates viral entry into the host cell. To identify possible antibody binding sites, we performed multi-microsecond molecular dynamics simulations of a 4.1 million atom s...

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Detalles Bibliográficos
Autores principales:	Sikora, Mateusz, von Bülow, Sören, Blanc, Florian E. C., Gecht, Michael, Covino, Roberto, Hummer, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016105/ https://www.ncbi.nlm.nih.gov/pubmed/33793546 http://dx.doi.org/10.1371/journal.pcbi.1008790

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