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AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides
[Image: see text] We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.
Autores principales: | Acevedo-Jake, Amanda, Ball, Andrew T., Galli, Marzia, Kukwikila, Mikiembo, Denis, Mathieu, Singleton, Daniel G., Tavassoli, Ali, Goldup, Stephen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016193/ https://www.ncbi.nlm.nih.gov/pubmed/32155338 http://dx.doi.org/10.1021/jacs.0c01670 |
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