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Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial
BACKGROUND: Neurodegenerative diseases are sporadic hereditary conditions characterized by progressive dysfunction of the nervous system. Among the symptoms, vestibulopathy is one of the causes of discomfort and a decrease in quality of life. Hereditary spastic paraplegia is a heterogeneous group of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016341/ https://www.ncbi.nlm.nih.gov/pubmed/33793609 http://dx.doi.org/10.1371/journal.pone.0249095 |
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author | Zeigelboim, Bianca Simone José, Maria Renata dos Santos, Geslaine Janaina Bueno Severiano, Maria Izabel Rodrigues Teive, Hélio Afonso Ghizoni Stechman-Neto, José Santos, Rosane Sampaio de Araújo, Cristiano Miranda Cavalcante-Leão, Bianca Lopes |
author_facet | Zeigelboim, Bianca Simone José, Maria Renata dos Santos, Geslaine Janaina Bueno Severiano, Maria Izabel Rodrigues Teive, Hélio Afonso Ghizoni Stechman-Neto, José Santos, Rosane Sampaio de Araújo, Cristiano Miranda Cavalcante-Leão, Bianca Lopes |
author_sort | Zeigelboim, Bianca Simone |
collection | PubMed |
description | BACKGROUND: Neurodegenerative diseases are sporadic hereditary conditions characterized by progressive dysfunction of the nervous system. Among the symptoms, vestibulopathy is one of the causes of discomfort and a decrease in quality of life. Hereditary spastic paraplegia is a heterogeneous group of hereditary degenerative diseases involving the disorder of a single gene and is characterized by the progressive retrograde degeneration of fibers in the spinal cord. OBJECTIVE: To determine the benefits of vestibular rehabilitation involving virtual reality by comparing pre intervention and post intervention assessments in individuals with hereditary spastic paraplegia. METHODS: In this randomized controlled clinical trial from the Rebec platform RBR-3jmx67 in which allocation concealment was performed and the evaluators be blinded will be included. The participants will include 40 patients diagnosed with hereditary spastic paraplegia. The interventions will include vestibular rehabilitation with virtual reality using the Wii(®) console, Wii-Remote and Wii Balance Board (Nintendo), and the studies will include pre- and post intervention assessments. Group I will include twenty volunteers who performed balance games. Group II will include twenty volunteers who performed balance games and muscle strength games. The games lasted from 30 minutes to an hour, and the sessions were performed twice a week for 10 weeks (total: 20 sessions). RESULTS: This study provides a definitive assessment of the effectiveness of a virtual reality vestibular rehabilitation program in halting the progression of hereditary spastic paraplegia, and this treatment can be personalized and affordable. CONCLUSION: The study will determine whether a vestibular rehabilitation program with the Nintendo Wii(®) involving virtual reality can reduce the progressive effect of hereditary spastic paraplegia and serve as an alternative treatment option that is accessible and inexpensive. Rebec platform trial: RBR-3JMX67. |
format | Online Article Text |
id | pubmed-8016341 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-80163412021-04-08 Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial Zeigelboim, Bianca Simone José, Maria Renata dos Santos, Geslaine Janaina Bueno Severiano, Maria Izabel Rodrigues Teive, Hélio Afonso Ghizoni Stechman-Neto, José Santos, Rosane Sampaio de Araújo, Cristiano Miranda Cavalcante-Leão, Bianca Lopes PLoS One Registered Report Protocol BACKGROUND: Neurodegenerative diseases are sporadic hereditary conditions characterized by progressive dysfunction of the nervous system. Among the symptoms, vestibulopathy is one of the causes of discomfort and a decrease in quality of life. Hereditary spastic paraplegia is a heterogeneous group of hereditary degenerative diseases involving the disorder of a single gene and is characterized by the progressive retrograde degeneration of fibers in the spinal cord. OBJECTIVE: To determine the benefits of vestibular rehabilitation involving virtual reality by comparing pre intervention and post intervention assessments in individuals with hereditary spastic paraplegia. METHODS: In this randomized controlled clinical trial from the Rebec platform RBR-3jmx67 in which allocation concealment was performed and the evaluators be blinded will be included. The participants will include 40 patients diagnosed with hereditary spastic paraplegia. The interventions will include vestibular rehabilitation with virtual reality using the Wii(®) console, Wii-Remote and Wii Balance Board (Nintendo), and the studies will include pre- and post intervention assessments. Group I will include twenty volunteers who performed balance games. Group II will include twenty volunteers who performed balance games and muscle strength games. The games lasted from 30 minutes to an hour, and the sessions were performed twice a week for 10 weeks (total: 20 sessions). RESULTS: This study provides a definitive assessment of the effectiveness of a virtual reality vestibular rehabilitation program in halting the progression of hereditary spastic paraplegia, and this treatment can be personalized and affordable. CONCLUSION: The study will determine whether a vestibular rehabilitation program with the Nintendo Wii(®) involving virtual reality can reduce the progressive effect of hereditary spastic paraplegia and serve as an alternative treatment option that is accessible and inexpensive. Rebec platform trial: RBR-3JMX67. Public Library of Science 2021-04-01 /pmc/articles/PMC8016341/ /pubmed/33793609 http://dx.doi.org/10.1371/journal.pone.0249095 Text en © 2021 Zeigelboim et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Registered Report Protocol Zeigelboim, Bianca Simone José, Maria Renata dos Santos, Geslaine Janaina Bueno Severiano, Maria Izabel Rodrigues Teive, Hélio Afonso Ghizoni Stechman-Neto, José Santos, Rosane Sampaio de Araújo, Cristiano Miranda Cavalcante-Leão, Bianca Lopes Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial |
title | Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial |
title_full | Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial |
title_fullStr | Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial |
title_full_unstemmed | Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial |
title_short | Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial |
title_sort | balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: protocol for a clinical trial |
topic | Registered Report Protocol |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016341/ https://www.ncbi.nlm.nih.gov/pubmed/33793609 http://dx.doi.org/10.1371/journal.pone.0249095 |
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