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Outcomes of Surgical Excision and High-Dose-Rate Brachytherapy for Earlobe Keloids

BACKGROUND: Radiotherapy as an adjuvant therapy to surgical resection has shown variable rates of recurrence treating earlobe keloids. The purpose of this study was to describe our experience with surgical excision followed by high-dose-rate brachytherapy and present our outcomes after 24 months of...

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Autores principales: Fuenmayor, Pedro, Quiñonez, Hector, Salas, Reinaldo, Pujadas, Zoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society for Plastic Surgeons 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016371/
https://www.ncbi.nlm.nih.gov/pubmed/33833958
http://dx.doi.org/10.29252/wjps.10.1.78
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author Fuenmayor, Pedro
Quiñonez, Hector
Salas, Reinaldo
Pujadas, Zoe
author_facet Fuenmayor, Pedro
Quiñonez, Hector
Salas, Reinaldo
Pujadas, Zoe
author_sort Fuenmayor, Pedro
collection PubMed
description BACKGROUND: Radiotherapy as an adjuvant therapy to surgical resection has shown variable rates of recurrence treating earlobe keloids. The purpose of this study was to describe our experience with surgical excision followed by high-dose-rate brachytherapy and present our outcomes after 24 months of follow-up. METHODS: Retrospective chart of 14 patients with 14 earlobe keloids treated with surgical excision followed by high-dose-rate brachytherapy, between January 2015 and May 2016 were enrolled. Database included demographics, Fitzpatrick skin type, laterality, lesion size, and follow-up visits information. Outcomes were assessed in terms of keloid recurrence rates, complications, and patient subjective aesthetical result satisfaction after 24 months of follow-up. RESULTS: All procedures were completed without complications. Three patients experienced keloid recurrence after 6 (14.28%) and 12 months (7.14%). Three patients experienced mild signs of self-limited post-radiation dermatitis. Self-assessment of aesthetical result was considered “very good” in 71.43% of patients. CONCLUSION: Surgical excision followed by high-dose-rate brachytherapy is secure and effective to treat earlobe keloids, and can be considered a first line combined treatment. Larger clinical trials comparing different irradiation protocols are still needed.
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spelling pubmed-80163712021-04-07 Outcomes of Surgical Excision and High-Dose-Rate Brachytherapy for Earlobe Keloids Fuenmayor, Pedro Quiñonez, Hector Salas, Reinaldo Pujadas, Zoe World J Plast Surg Original Article BACKGROUND: Radiotherapy as an adjuvant therapy to surgical resection has shown variable rates of recurrence treating earlobe keloids. The purpose of this study was to describe our experience with surgical excision followed by high-dose-rate brachytherapy and present our outcomes after 24 months of follow-up. METHODS: Retrospective chart of 14 patients with 14 earlobe keloids treated with surgical excision followed by high-dose-rate brachytherapy, between January 2015 and May 2016 were enrolled. Database included demographics, Fitzpatrick skin type, laterality, lesion size, and follow-up visits information. Outcomes were assessed in terms of keloid recurrence rates, complications, and patient subjective aesthetical result satisfaction after 24 months of follow-up. RESULTS: All procedures were completed without complications. Three patients experienced keloid recurrence after 6 (14.28%) and 12 months (7.14%). Three patients experienced mild signs of self-limited post-radiation dermatitis. Self-assessment of aesthetical result was considered “very good” in 71.43% of patients. CONCLUSION: Surgical excision followed by high-dose-rate brachytherapy is secure and effective to treat earlobe keloids, and can be considered a first line combined treatment. Larger clinical trials comparing different irradiation protocols are still needed. Iranian Society for Plastic Surgeons 2021-01 /pmc/articles/PMC8016371/ /pubmed/33833958 http://dx.doi.org/10.29252/wjps.10.1.78 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Fuenmayor, Pedro
Quiñonez, Hector
Salas, Reinaldo
Pujadas, Zoe
Outcomes of Surgical Excision and High-Dose-Rate Brachytherapy for Earlobe Keloids
title Outcomes of Surgical Excision and High-Dose-Rate Brachytherapy for Earlobe Keloids
title_full Outcomes of Surgical Excision and High-Dose-Rate Brachytherapy for Earlobe Keloids
title_fullStr Outcomes of Surgical Excision and High-Dose-Rate Brachytherapy for Earlobe Keloids
title_full_unstemmed Outcomes of Surgical Excision and High-Dose-Rate Brachytherapy for Earlobe Keloids
title_short Outcomes of Surgical Excision and High-Dose-Rate Brachytherapy for Earlobe Keloids
title_sort outcomes of surgical excision and high-dose-rate brachytherapy for earlobe keloids
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016371/
https://www.ncbi.nlm.nih.gov/pubmed/33833958
http://dx.doi.org/10.29252/wjps.10.1.78
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