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LDpred2: better, faster, stronger

MOTIVATION: Polygenic scores have become a central tool in human genetics research. LDpred is a popular method for deriving polygenic scores based on summary statistics and a matrix of correlation between genetic variants. However, LDpred has limitations that may reduce its predictive performance. R...

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Detalles Bibliográficos
Autores principales: Privé, Florian, Arbel, Julyan, Vilhjálmsson, Bjarni J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016455/
https://www.ncbi.nlm.nih.gov/pubmed/33326037
http://dx.doi.org/10.1093/bioinformatics/btaa1029