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LDpred2: better, faster, stronger
MOTIVATION: Polygenic scores have become a central tool in human genetics research. LDpred is a popular method for deriving polygenic scores based on summary statistics and a matrix of correlation between genetic variants. However, LDpred has limitations that may reduce its predictive performance. R...
Autores principales: | Privé, Florian, Arbel, Julyan, Vilhjálmsson, Bjarni J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016455/ https://www.ncbi.nlm.nih.gov/pubmed/33326037 http://dx.doi.org/10.1093/bioinformatics/btaa1029 |
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