Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies

Rab GTPases are molecular switches that regulate membrane trafficking in all cells. Neurons have particular demands on membrane trafficking and express numerous Rab GTPases of unknown function. Here, we report the generation and characterization of molecularly defined null mutants for all 26 rab gen...

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Detalles Bibliográficos
Autores principales: Kohrs, Friederike E, Daumann, Ilsa-Maria, Pavlovic, Bojana, Jin, Eugene Jennifer, Kiral, F Ridvan, Lin, Shih-Ching, Port, Filip, Wolfenberg, Heike, Mathejczyk, Thomas F, Linneweber, Gerit A, Chan, Chih-Chiang, Boutros, Michael, Hiesinger, P Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016483/
https://www.ncbi.nlm.nih.gov/pubmed/33666175
http://dx.doi.org/10.7554/eLife.59594

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