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Virxicon: a lexicon of viral sequences

MOTIVATION: Viruses are the most abundant biological entities and constitute a large reservoir of genetic diversity. In recent years, knowledge about them has increased significantly as a result of dynamic development in life sciences and rapid technological progress. This knowledge is scattered acr...

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Autores principales: Kudla, Mateusz, Gutowska, Kaja, Synak, Jaroslaw, Weber, Mirko, Bohnsack, Katrin Sophie, Lukasiak, Piotr, Villmann, Thomas, Blazewicz, Jacek, Szachniuk, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016492/
https://www.ncbi.nlm.nih.gov/pubmed/33367605
http://dx.doi.org/10.1093/bioinformatics/btaa1066
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author Kudla, Mateusz
Gutowska, Kaja
Synak, Jaroslaw
Weber, Mirko
Bohnsack, Katrin Sophie
Lukasiak, Piotr
Villmann, Thomas
Blazewicz, Jacek
Szachniuk, Marta
author_facet Kudla, Mateusz
Gutowska, Kaja
Synak, Jaroslaw
Weber, Mirko
Bohnsack, Katrin Sophie
Lukasiak, Piotr
Villmann, Thomas
Blazewicz, Jacek
Szachniuk, Marta
author_sort Kudla, Mateusz
collection PubMed
description MOTIVATION: Viruses are the most abundant biological entities and constitute a large reservoir of genetic diversity. In recent years, knowledge about them has increased significantly as a result of dynamic development in life sciences and rapid technological progress. This knowledge is scattered across various data repositories, making a comprehensive analysis of viral data difficult. RESULTS: In response to the need for gathering a comprehensive knowledge of viruses and viral sequences, we developed Virxicon, a lexicon of all experimentally acquired sequences for RNA and DNA viruses. The ability to quickly obtain data for entire viral groups, searching sequences by levels of taxonomic hierarchy—according to the Baltimore classification and ICTV taxonomy—and tracking the distribution of viral data and its growth over time are unique features of our database compared to the other tools. AVAILABILITYAND IMPLEMENTATION: Virxicon is a publicly available resource, updated weekly. It has an intuitive web interface and can be freely accessed at http://virxicon.cs.put.poznan.pl/.
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spelling pubmed-80164922021-04-07 Virxicon: a lexicon of viral sequences Kudla, Mateusz Gutowska, Kaja Synak, Jaroslaw Weber, Mirko Bohnsack, Katrin Sophie Lukasiak, Piotr Villmann, Thomas Blazewicz, Jacek Szachniuk, Marta Bioinformatics Original Papers MOTIVATION: Viruses are the most abundant biological entities and constitute a large reservoir of genetic diversity. In recent years, knowledge about them has increased significantly as a result of dynamic development in life sciences and rapid technological progress. This knowledge is scattered across various data repositories, making a comprehensive analysis of viral data difficult. RESULTS: In response to the need for gathering a comprehensive knowledge of viruses and viral sequences, we developed Virxicon, a lexicon of all experimentally acquired sequences for RNA and DNA viruses. The ability to quickly obtain data for entire viral groups, searching sequences by levels of taxonomic hierarchy—according to the Baltimore classification and ICTV taxonomy—and tracking the distribution of viral data and its growth over time are unique features of our database compared to the other tools. AVAILABILITYAND IMPLEMENTATION: Virxicon is a publicly available resource, updated weekly. It has an intuitive web interface and can be freely accessed at http://virxicon.cs.put.poznan.pl/. Oxford University Press 2020-12-26 /pmc/articles/PMC8016492/ /pubmed/33367605 http://dx.doi.org/10.1093/bioinformatics/btaa1066 Text en © The Author(s) 2020. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Papers
Kudla, Mateusz
Gutowska, Kaja
Synak, Jaroslaw
Weber, Mirko
Bohnsack, Katrin Sophie
Lukasiak, Piotr
Villmann, Thomas
Blazewicz, Jacek
Szachniuk, Marta
Virxicon: a lexicon of viral sequences
title Virxicon: a lexicon of viral sequences
title_full Virxicon: a lexicon of viral sequences
title_fullStr Virxicon: a lexicon of viral sequences
title_full_unstemmed Virxicon: a lexicon of viral sequences
title_short Virxicon: a lexicon of viral sequences
title_sort virxicon: a lexicon of viral sequences
topic Original Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016492/
https://www.ncbi.nlm.nih.gov/pubmed/33367605
http://dx.doi.org/10.1093/bioinformatics/btaa1066
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