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Virxicon: a lexicon of viral sequences
MOTIVATION: Viruses are the most abundant biological entities and constitute a large reservoir of genetic diversity. In recent years, knowledge about them has increased significantly as a result of dynamic development in life sciences and rapid technological progress. This knowledge is scattered acr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016492/ https://www.ncbi.nlm.nih.gov/pubmed/33367605 http://dx.doi.org/10.1093/bioinformatics/btaa1066 |
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author | Kudla, Mateusz Gutowska, Kaja Synak, Jaroslaw Weber, Mirko Bohnsack, Katrin Sophie Lukasiak, Piotr Villmann, Thomas Blazewicz, Jacek Szachniuk, Marta |
author_facet | Kudla, Mateusz Gutowska, Kaja Synak, Jaroslaw Weber, Mirko Bohnsack, Katrin Sophie Lukasiak, Piotr Villmann, Thomas Blazewicz, Jacek Szachniuk, Marta |
author_sort | Kudla, Mateusz |
collection | PubMed |
description | MOTIVATION: Viruses are the most abundant biological entities and constitute a large reservoir of genetic diversity. In recent years, knowledge about them has increased significantly as a result of dynamic development in life sciences and rapid technological progress. This knowledge is scattered across various data repositories, making a comprehensive analysis of viral data difficult. RESULTS: In response to the need for gathering a comprehensive knowledge of viruses and viral sequences, we developed Virxicon, a lexicon of all experimentally acquired sequences for RNA and DNA viruses. The ability to quickly obtain data for entire viral groups, searching sequences by levels of taxonomic hierarchy—according to the Baltimore classification and ICTV taxonomy—and tracking the distribution of viral data and its growth over time are unique features of our database compared to the other tools. AVAILABILITYAND IMPLEMENTATION: Virxicon is a publicly available resource, updated weekly. It has an intuitive web interface and can be freely accessed at http://virxicon.cs.put.poznan.pl/. |
format | Online Article Text |
id | pubmed-8016492 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-80164922021-04-07 Virxicon: a lexicon of viral sequences Kudla, Mateusz Gutowska, Kaja Synak, Jaroslaw Weber, Mirko Bohnsack, Katrin Sophie Lukasiak, Piotr Villmann, Thomas Blazewicz, Jacek Szachniuk, Marta Bioinformatics Original Papers MOTIVATION: Viruses are the most abundant biological entities and constitute a large reservoir of genetic diversity. In recent years, knowledge about them has increased significantly as a result of dynamic development in life sciences and rapid technological progress. This knowledge is scattered across various data repositories, making a comprehensive analysis of viral data difficult. RESULTS: In response to the need for gathering a comprehensive knowledge of viruses and viral sequences, we developed Virxicon, a lexicon of all experimentally acquired sequences for RNA and DNA viruses. The ability to quickly obtain data for entire viral groups, searching sequences by levels of taxonomic hierarchy—according to the Baltimore classification and ICTV taxonomy—and tracking the distribution of viral data and its growth over time are unique features of our database compared to the other tools. AVAILABILITYAND IMPLEMENTATION: Virxicon is a publicly available resource, updated weekly. It has an intuitive web interface and can be freely accessed at http://virxicon.cs.put.poznan.pl/. Oxford University Press 2020-12-26 /pmc/articles/PMC8016492/ /pubmed/33367605 http://dx.doi.org/10.1093/bioinformatics/btaa1066 Text en © The Author(s) 2020. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Original Papers Kudla, Mateusz Gutowska, Kaja Synak, Jaroslaw Weber, Mirko Bohnsack, Katrin Sophie Lukasiak, Piotr Villmann, Thomas Blazewicz, Jacek Szachniuk, Marta Virxicon: a lexicon of viral sequences |
title | Virxicon: a lexicon of viral sequences |
title_full | Virxicon: a lexicon of viral sequences |
title_fullStr | Virxicon: a lexicon of viral sequences |
title_full_unstemmed | Virxicon: a lexicon of viral sequences |
title_short | Virxicon: a lexicon of viral sequences |
title_sort | virxicon: a lexicon of viral sequences |
topic | Original Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016492/ https://www.ncbi.nlm.nih.gov/pubmed/33367605 http://dx.doi.org/10.1093/bioinformatics/btaa1066 |
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