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Vitamin K(2) protects against Aβ42-induced neurotoxicity by activating autophagy and improving mitochondrial function in Drosophila

OBJECTIVE: Alzheimer disease is characterized by progressive decline in cognitive function due to neurodegeneration induced by accumulation of Aβ and hyperphosphorylated tau protein. This study was conducted to explore the protective effect of vitamin K(2) against Aβ42-induced neurotoxicity. METHODS...

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Detalles Bibliográficos
Autores principales: Lin, Xiaohui, Wen, Xueyi, Wei, Zaiwa, Guo, Keyi, Shi, Fang, Huang, Tingting, Wang, Wenjing, Zheng, Jinou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016515/
https://www.ncbi.nlm.nih.gov/pubmed/33788812
http://dx.doi.org/10.1097/WNR.0000000000001599

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