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Vitamin K(2) protects against Aβ42-induced neurotoxicity by activating autophagy and improving mitochondrial function in Drosophila
OBJECTIVE: Alzheimer disease is characterized by progressive decline in cognitive function due to neurodegeneration induced by accumulation of Aβ and hyperphosphorylated tau protein. This study was conducted to explore the protective effect of vitamin K(2) against Aβ42-induced neurotoxicity. METHODS...
Autores principales: | Lin, Xiaohui, Wen, Xueyi, Wei, Zaiwa, Guo, Keyi, Shi, Fang, Huang, Tingting, Wang, Wenjing, Zheng, Jinou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016515/ https://www.ncbi.nlm.nih.gov/pubmed/33788812 http://dx.doi.org/10.1097/WNR.0000000000001599 |
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