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Vitronectin‐activated αvβ3 and αvβ5 integrin signalling specifies haematopoietic fate in human pluripotent stem cells

OBJECTIVES: Vitronectin (VTN) has been widely used for the maintenance and expansion of human pluripotent stem cells (hPSCs) as feeder‐free conditions. However, the effect of VTN on hPSC differentiation remains unclear. Here, we investigated the role of VTN in early haematopoietic development of hPS...

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Detalles Bibliográficos
Autores principales: Shen, Jun, Zhu, Yaoyao, Zhang, Shuo, Lyu, Shuzhen, Lyu, Cuicui, Feng, Zicen, Hoyle, Dixie L., Wang, Zack Z., Cheng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016644/
https://www.ncbi.nlm.nih.gov/pubmed/33656760
http://dx.doi.org/10.1111/cpr.13012