APOE alleles’ association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos‐investigation of neurocognitive aging (HCHS/SOL)

INTRODUCTION: Apolipoprotein E (APOE) alleles are associated with cognitive decline, mild cognitive impairment (MCI), and Alzheimer's disease in Whites, but have weaker and inconsistent effects reported in Latinos. We hypothesized that this heterogeneity is due to ancestry‐specific genetic effe...

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Detalles Bibliográficos
Autores principales: Granot‐Hershkovitz, Einat, Tarraf, Wassim, Kurniansyah, Nuzulul, Daviglus, Martha, Isasi, Carmen R., Kaplan, Robert, Lamar, Melissa, Perreira, Krista M., Wassertheil‐Smoller, Sylvia, Stickel, Ariana, Thyagarajan, Bharat, Zeng, Donglin, Fornage, Myriam, DeCarli, Charles S., González, Hector M., Sofer, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016734/
https://www.ncbi.nlm.nih.gov/pubmed/33155766
http://dx.doi.org/10.1002/alz.12205

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