Utidelone inhibits growth of colorectal cancer cells through ROS/JNK signaling pathway

Utidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue which was produced by genetic engineering. UTD1 has exhibited broad antitumor activity in multiple solid tumors. However, its activity and mechanism in colorectal cancer (CRC) remain to be studied. In this study, UT...

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Detalles Bibliográficos
Autores principales: Li, Fuli, Huang, Tinglei, Tang, Yao, Li, Qingli, Wang, Jianzheng, Cheng, Xiaojiao, Zhang, Wenhui, Zhang, Baiwen, Zhou, Cong, Tu, Shuiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016927/
https://www.ncbi.nlm.nih.gov/pubmed/33795638
http://dx.doi.org/10.1038/s41419-021-03619-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016927/
https://www.ncbi.nlm.nih.gov/pubmed/33795638
http://dx.doi.org/10.1038/s41419-021-03619-6

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