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Utidelone inhibits growth of colorectal cancer cells through ROS/JNK signaling pathway
Utidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue which was produced by genetic engineering. UTD1 has exhibited broad antitumor activity in multiple solid tumors. However, its activity and mechanism in colorectal cancer (CRC) remain to be studied. In this study, UT...
Autores principales: | Li, Fuli, Huang, Tinglei, Tang, Yao, Li, Qingli, Wang, Jianzheng, Cheng, Xiaojiao, Zhang, Wenhui, Zhang, Baiwen, Zhou, Cong, Tu, Shuiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016927/ https://www.ncbi.nlm.nih.gov/pubmed/33795638 http://dx.doi.org/10.1038/s41419-021-03619-6 |
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