Systems serology detects functionally distinct coronavirus antibody features in children and elderly

The hallmarks of COVID-19 are higher pathogenicity and mortality in the elderly compared to children. Examining baseline SARS-CoV-2 cross-reactive immunological responses, induced by circulating human coronaviruses (hCoVs), is needed to understand such divergent clinical outcomes. Here we show analy...

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Detalles Bibliográficos
Autores principales: Selva, Kevin J., van de Sandt, Carolien E., Lemke, Melissa M., Lee, Christina Y., Shoffner, Suzanne K., Chua, Brendon Y., Davis, Samantha K., Nguyen, Thi H. O., Rowntree, Louise C., Hensen, Luca, Koutsakos, Marios, Wong, Chinn Yi, Mordant, Francesca, Jackson, David C., Flanagan, Katie L., Crowe, Jane, Tosif, Shidan, Neeland, Melanie R., Sutton, Philip, Licciardi, Paul V., Crawford, Nigel W., Cheng, Allen C., Doolan, Denise L., Amanat, Fatima, Krammer, Florian, Chappell, Keith, Modhiran, Naphak, Watterson, Daniel, Young, Paul, Lee, Wen Shi, Wines, Bruce D., Mark Hogarth, P., Esterbauer, Robyn, Kelly, Hannah G., Tan, Hyon-Xhi, Juno, Jennifer A., Wheatley, Adam K., Kent, Stephen J., Arnold, Kelly B., Kedzierska, Katherine, Chung, Amy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016934/
https://www.ncbi.nlm.nih.gov/pubmed/33795692
http://dx.doi.org/10.1038/s41467-021-22236-7

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