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Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network

COPII mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Five essential proteins assemble into a two-layer architecture, with the inner layer thought to regulate coat assembly and cargo recruitment, and the outer coat forming cages assumed to scaffold membrane curvature. He...

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Detalles Bibliográficos
Autores principales: Hutchings, Joshua, Stancheva, Viktoriya G., Brown, Nick R., Cheung, Alan C. M., Miller, Elizabeth A., Zanetti, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016994/
https://www.ncbi.nlm.nih.gov/pubmed/33795673
http://dx.doi.org/10.1038/s41467-021-22110-6